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UNITING THE WORLD OF FITNESS
Health Club Management

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News

Research provides new evidence of how exercise can counter diabetes damage

Scientists at Medical College of Georgia have found that exercise can help enable angiogenesis
The formation of new blood vessels could reverse the damage caused to vessels by diabetes
Exercise also increased the amount of the extracellular superoxide dismutase
The findings of the study were published in The FASEB Journal

Being physically active can counter the damage of diabetes by enabling the activation of a natural system that grows new blood vessels.

Diabetes not only damages existing blood vessels, but it also hinders the innate ability to grow new ones in the face of disease and injury.

Scientists at Medical College of Georgia (MCG), however, have found that exercise can help enable angiogenesis – the formation of new blood vessels – which in turn reverses the damage caused by diabetes.

In a study published in The FASEB Journal, a team at MCG's Vascular Biology Center found the first evidence that in the face of diabetes, even one 45-minute session of moderate-intensity exercise enables more exosomes, submicroscopic packages filled with biologically active cargo, to deliver directly to those cells more of the protein, ATP7A, which can set angiogenesis in motion.

Exercise also increased the amount of the extracellular superoxide dismutase (SOD3), an important natural antioxidant produced by vascular smooth muscle cells in the walls of blood vessels, as well as skeletal muscle cells, which helps maintain healthy levels of reactive oxygen species.

Dr. Tohru Fukai, MCG vascular biologist and cardiologist and lead author of the study, said: "ATP7A levels are reduced in diabetes and we now have some of the first evidence that exosomes among those with type 2 diabetes actually impair angiogenesis.

"Synthetic exosomes, already under study as drug-delivery mechanisms, could one day work as an “exercise mimetic” to improve patients’ ability to grow new blood vessels when diabetes has damaged their innate ability."

To read the full research report, click here.

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News

Research provides new evidence of how exercise can counter diabetes damage

Scientists at Medical College of Georgia have found that exercise can help enable angiogenesis
The formation of new blood vessels could reverse the damage caused to vessels by diabetes
Exercise also increased the amount of the extracellular superoxide dismutase
The findings of the study were published in The FASEB Journal

Being physically active can counter the damage of diabetes by enabling the activation of a natural system that grows new blood vessels.

Diabetes not only damages existing blood vessels, but it also hinders the innate ability to grow new ones in the face of disease and injury.

Scientists at Medical College of Georgia (MCG), however, have found that exercise can help enable angiogenesis – the formation of new blood vessels – which in turn reverses the damage caused by diabetes.

In a study published in The FASEB Journal, a team at MCG's Vascular Biology Center found the first evidence that in the face of diabetes, even one 45-minute session of moderate-intensity exercise enables more exosomes, submicroscopic packages filled with biologically active cargo, to deliver directly to those cells more of the protein, ATP7A, which can set angiogenesis in motion.

Exercise also increased the amount of the extracellular superoxide dismutase (SOD3), an important natural antioxidant produced by vascular smooth muscle cells in the walls of blood vessels, as well as skeletal muscle cells, which helps maintain healthy levels of reactive oxygen species.

Dr. Tohru Fukai, MCG vascular biologist and cardiologist and lead author of the study, said: "ATP7A levels are reduced in diabetes and we now have some of the first evidence that exosomes among those with type 2 diabetes actually impair angiogenesis.

"Synthetic exosomes, already under study as drug-delivery mechanisms, could one day work as an “exercise mimetic” to improve patients’ ability to grow new blood vessels when diabetes has damaged their innate ability."

To read the full research report, click here.

Related news

Stay strong, live long

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Spending just 30-60 minutes a week on muscle strengthening exercises can significantly reduce the risk ...

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An international team of scientists has carried out a study to help gauge how and ...

News

The Leisure Database Company (TLDB) has revealed its State of the Fitness Industry Report UK
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A new physical activity programme called Big Sister has been launched in the UK to
Go Fit has been selected by the United Nations Economic Commission for Europe (UNECE) as
Ness, a US startup that is developing a range of wellness-driven credit cards, has launched
Following a history of supporting US military and service members, F45 has announced a new
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More than 100 industry delegates met in person at the annual active-net event at Eastwood
Hyatt is piloting private gyms in five of its US hotels as part of its
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Active Nottingham, part of Nottingham City Council, has released a children’s book called Can We
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Fitness industry veteran Harm Tegelaars has returned to the fitness industry by joining the board
Innovatise UK Ltd
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Les Mills
Les Mills
1 - 20 of 12,212
HCM Magazine
Write to reply
Fuel the debate about issues and opportunities across the industry. We’d love to hear from you – [email protected]
HCM Magazine
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HCM Magazine
Sponsored
Yate Leisure is one of the largest sites in Circadian Trust’s portfolio, with around 4,000 members. Ben Beasley, director of commercial development, explains why they were an early adopter of Technogym Biocircuit, and how the offer has evolved
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HCM magazine
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Featured supplier news
Featured supplier news: Magicline celebrates UK market entry at Elevate
With a focus on globalisation, Magicline has officially launched its software in the UK. As Europe’s leading gym management software company, the company strives to provide the best tools for gym owners to be successful, win new members and elevate their businesses.
Featured supplier news
Featured supplier news: Virtuagym raises €3m investment to fuel innovation in health and fitness technology
Global fitness technology provider Virtuagym has raised a new €3m investment from Icecat, an Amsterdam-based technology company which invests in innovative technology organisations.
Featured operator news
Featured operator news: Serco Leisure wins 10-year Mansfield contract
Following a competitive tendering process, Serco Leisure and its partner More Leisure Community Trust Limited (MLCT) have been awarded a 10-year contract by Mansfield District Council to operate three centres in the town, starting 1 May 2022.
Featured operator news
Featured operator news: Everyone Active to launch new exercise classes to reduce gender gap
As part of their work to break down the barriers that deter women and girls from participating in sport and physical activity, Everyone Active has teamed up with EMD UK to launch new exercise classes linked to the This Girl Can campaign.
Video Gallery
Sport Alliance GmbH
Total Vibration Solutions / Floors 4 Gyms / TVS Sports Surfaces
Mindbody, Inc
Company profiles
Company profile: RISE Fitness Franchise
RISE is a brand-new franchise created to fill an emerging gap. Outdoor workouts have become ...
Company profiles
Company profile: Mindbody
Mindbody is the leading technology platform for the wellness industry, featuring an app that allows ...
Catalogue Gallery
Click on a catalogue to view it online
Directory
Flooring
Total Vibration Solutions / TVS Sports Surfaces: Flooring
On demand
Fitness On Demand: On demand
Skincare
Sothys: Skincare
Wearable technology solutions
MyZone: Wearable technology solutions
Salt therapy products
Saltability: Salt therapy products
Fitness equipment
A Panatta Sport Srl: Fitness equipment
Management software
Premier Software Solutions: Management software
Spa software
SpaBooker: Spa software
trade associations
International SPA Association - iSPA: trade associations
Architects/designers
Zynk Design Consultants: Architects/designers
Property & Tenders
Pendine Sands, Carmarthenshire
Carmarthenshire County Council
Property & Tenders
Runcorn
Halton Borough Council
Property & Tenders
Diary dates
15-16 Jun 2022
ExCeL London, London, United Kingdom
Diary dates
30-30 Jun 2022
The ICC, Birmingham, Birmingham , United Kingdom
Diary dates
12-13 Sep 2022
Wyndham Lake Buena Vista Disney Springs® Resort, Lake Buena Vista, United States
Diary dates
25-28 Oct 2022
Messe Stuttgart, Germany
Diary dates
25-28 Oct 2022
Ibiza, Ibiza, Spain
Diary dates
01-07 Dec 2022
tbc, Dunedin, New Zealand
Diary dates
17-18 Mar 2023
Tobacco Dock, London, United Kingdom
Diary dates
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