GET HCM
magazine
Sign up for the FREE digital edition of HCM magazine and also get the HCM ezine and breaking news email alerts.
Not right now, thanksclose this window
Les Mills International
Les Mills International
Les Mills International
Follow Health Club Management on Twitter Like Health Club Management on Facebook Join the discussion with Health Club Management on LinkedIn Follow Health Club Management on Instagram
UNITING THE WORLD OF FITNESS
Health Club Management

Health Club Management

features

Research: Exercise can counter diabetes damage

Being physically active can heal damage caused by diabetes, enabling the activation of a natural system that grows new blood vessels, according to research in the US

Published in Health Club Management 2022 issue 4
One 45 minute ssession was enough to register a positive impact / Shutterstock/Juice Flair
One 45 minute ssession was enough to register a positive impact / Shutterstock/Juice Flair
Exercise can simulate the growth of new blood vessels when existing ones are ravaged by diabetes

Diabetes not only damages existing blood vessels but also hinders the body’s innate ability to grow new ones in the face of disease and injury.

Scientists at Medical College of Georgia (MCG), however, have found that exercise can help enable angiogenesis – the formation of new blood vessels – which in turn reverses the damage caused by diabetes.

In a study published in The FASEB Journal, a team at MCG’s Vascular Biology Center found the first evidence that in the face of diabetes, even one 45-minute session of moderate-intensity exercise prompts the release of more exosomes into the blood to deliver more of the protein ATP7A directly to cells, which can set angiogenesis in motion. Exosomes are submicroscopic packages filled with biologically active ‘cargo’.

One cardio session
In a sample of healthy 50-something-year-olds, one cardio session increased levels of ATP7A in the exosomes that attached to endothelial cells.

Exercise also increased levels of extracellular superoxide dismutase (SOD3), an important natural antioxidant produced by vascular smooth muscle cells in the walls of blood vessels, as well as skeletal muscle cells, which helps maintain healthy levels of reactive oxygen species or ROS.

ROS is a natural byproduct of our use of oxygen that is an important cell signal, enabling a variety of functions. But in diabetes, high blood sugar levels result in higher ROS levels that instead hinder important normal functions.

Dr Tohru Fukai, MCG vascular biologist and cardiologist and lead author of the study, said: “ATP7A levels are reduced in diabetes and we now have some of the first evidence that exosomes actually impair angiogenesis among those with Type 2 diabetes.

Read the full research report: Exercise improves angiogenic function of circulating exosomes in type 2 diabetes: Role of exosomal SOD3 at www.hcmmag.com/angiogenic

https://www.leisureopportunities.co.uk/images/2022/535084_535875.jpg
Exercise can stimulate the growth of new blood vessels when existing ones are ravaged by diabetes, find researchers
HCM magazine
As Elevate returns to the market, we talk to director Lucy Findlay about how the event has come together
HCM magazine
We were one of the first operators to use a cloud-based data lake – Snowflake – that now underpins the rollout of our Business Intelligence work
HCM magazine
From colour zones to personalised resistance, indoor bikes now offer smarter, more advanced features than ever before. Suppliers tell us how their models can revolutionise your indoor cycling programme
HCM Magazine
Sponsored
Everyone has the right to know about their own internal data, to enable and motivate them to take control of their own health
HCM Magazine
Flooring
Time for a flooring upgrade? Experts share their latest insights to inspire flooring projects of all types
HCM Magazine
Interview
The CEO of Women in Sport tells HCM about Big Sister, a new programme that’s working to overcome period poverty and get more girls active
HCM Magazine
HCM People
Despite industry challenges, there’s a fresh air of positivity
HCM Magazine
Facilities
What to do when your changing rooms need a refresh, but your budget is stretched? These specialists share their top tips for easy upgrades that won’t break the bank
HCM Magazine
Research
Bryce Hastings, head of research at Les Mills, explains the latest research into exercise motivation, giving tips on how to engage hard-to-reach members
HCM Magazine
Research
Being physically active can heal damage caused by diabetes, enabling the activation of a natural system that grows new blood vessels, according to research in the US
HCM Magazine
Latest News
The best in the business from across the physical activity sector were honoured last night ...
Latest News
At UK Active’s Active Uprising event yesterday (30 June) in Birmingham, Hattie Jones, the head ...
Latest News
HCM understands researchers are moving closer to creating a pill to mimic some of the ...
Latest News
Establishing new data and insight services and strengthening relationships with both government and the NHS ...
Latest News
More than one in five (27 per cent) Americans belonged to a health club or ...
Latest News
Ultimate Performance (UP) – the private gym chain and PT business – has opened a ...
Latest News
Luxury hotel chain Mandarin Oriental has launched a new brand called Intelligent Movement to deliver ...
Latest News
Boutique fitness chain 1Rebel opens the doors to its tenth club today (Monday 27 June ...
Featured supplier news
Featured supplier news: How wearables-driven gamification will boost your business
It’s a known fact that gamification is an effective method to make everyday activities and work more fun.
Featured supplier news
Featured supplier news: EGYM announces integration with software provider Fisikal
EGYM has announced an integration with a leading UK-based software company Fisikal to enhance its capabilities to serve the needs of enterprise customers running multi-site operations.
Featured operator news
Featured operator news: Everyone Active to launch new exercise classes to reduce gender gap
As part of their work to break down the barriers that deter women and girls from participating in sport and physical activity, Everyone Active has teamed up with EMD UK to launch new exercise classes linked to the This Girl Can campaign.
Featured operator news
Featured operator news: New £42m Moorways Sports Village to open on 21 May
Everyone Active will open Moorways Sports Village to the public on Saturday 21 May with a grand opening weekend – in time for the half term holidays.
Video Gallery
Total Vibration Solutions / Floors 4 Gyms / TVS Sports Surfaces
Mindbody, Inc
Sport Alliance GmbH
Company profiles
Company profile: Future Fit
More than just a training provider, we offer a range of ready to go and ...
Company profiles
Company profile: Technogym UK Ltd
Technogym offers a complete ecosystem of connected smart equipment, digital services, on-demand training experiences and ...
Supplier Showcases
Supplier showcase - Pulse Fitness: trusted partner
Catalogue Gallery
Click on a catalogue to view it online
Directory
Fitness equipment
A Panatta Sport Srl: Fitness equipment
Flooring
Total Vibration Solutions / TVS Sports Surfaces: Flooring
Wearable technology solutions
MyZone: Wearable technology solutions
Architects/designers
Zynk Design Consultants: Architects/designers
Spa software
SpaBooker: Spa software
On demand
Fitness On Demand: On demand
Skincare
Comfort Zone - Davines S.p.A: Skincare
Salt therapy products
Himalayan Source: Salt therapy products
Whole body cryotherapy
Art of Cryo: Whole body cryotherapy
Lockers/interior design
Crown Sports Lockers: Lockers/interior design
Property & Tenders
Pendine Sands, Carmarthenshire
Carmarthenshire County Council
Property & Tenders
Runcorn
Halton Borough Council
Property & Tenders
Diary dates
12-13 Sep 2022
Wyndham Lake Buena Vista Disney Springs® Resort, Lake Buena Vista, United States
Diary dates
21-21 Sep 2022
Various, London, United Kingdom
Diary dates
25-28 Oct 2022
Messe Stuttgart, Germany
Diary dates
25-28 Oct 2022
Ibiza, Ibiza, Spain
Diary dates
01-07 Dec 2022
tbc, Dunedin, New Zealand
Diary dates
17-18 Mar 2023
Tobacco Dock, London, United Kingdom
Diary dates

features

Research: Exercise can counter diabetes damage

Being physically active can heal damage caused by diabetes, enabling the activation of a natural system that grows new blood vessels, according to research in the US

Published in Health Club Management 2022 issue 4
One 45 minute ssession was enough to register a positive impact / Shutterstock/Juice Flair
One 45 minute ssession was enough to register a positive impact / Shutterstock/Juice Flair
Exercise can simulate the growth of new blood vessels when existing ones are ravaged by diabetes

Diabetes not only damages existing blood vessels but also hinders the body’s innate ability to grow new ones in the face of disease and injury.

Scientists at Medical College of Georgia (MCG), however, have found that exercise can help enable angiogenesis – the formation of new blood vessels – which in turn reverses the damage caused by diabetes.

In a study published in The FASEB Journal, a team at MCG’s Vascular Biology Center found the first evidence that in the face of diabetes, even one 45-minute session of moderate-intensity exercise prompts the release of more exosomes into the blood to deliver more of the protein ATP7A directly to cells, which can set angiogenesis in motion. Exosomes are submicroscopic packages filled with biologically active ‘cargo’.

One cardio session
In a sample of healthy 50-something-year-olds, one cardio session increased levels of ATP7A in the exosomes that attached to endothelial cells.

Exercise also increased levels of extracellular superoxide dismutase (SOD3), an important natural antioxidant produced by vascular smooth muscle cells in the walls of blood vessels, as well as skeletal muscle cells, which helps maintain healthy levels of reactive oxygen species or ROS.

ROS is a natural byproduct of our use of oxygen that is an important cell signal, enabling a variety of functions. But in diabetes, high blood sugar levels result in higher ROS levels that instead hinder important normal functions.

Dr Tohru Fukai, MCG vascular biologist and cardiologist and lead author of the study, said: “ATP7A levels are reduced in diabetes and we now have some of the first evidence that exosomes actually impair angiogenesis among those with Type 2 diabetes.

Read the full research report: Exercise improves angiogenic function of circulating exosomes in type 2 diabetes: Role of exosomal SOD3 at www.hcmmag.com/angiogenic

https://www.leisureopportunities.co.uk/images/2022/535084_535875.jpg
Exercise can stimulate the growth of new blood vessels when existing ones are ravaged by diabetes, find researchers
Latest News
The best in the business from across the physical activity sector were honoured last night ...
Latest News
At UK Active’s Active Uprising event yesterday (30 June) in Birmingham, Hattie Jones, the head ...
Latest News
HCM understands researchers are moving closer to creating a pill to mimic some of the ...
Latest News
Establishing new data and insight services and strengthening relationships with both government and the NHS ...
Latest News
More than one in five (27 per cent) Americans belonged to a health club or ...
Latest News
Ultimate Performance (UP) – the private gym chain and PT business – has opened a ...
Latest News
Luxury hotel chain Mandarin Oriental has launched a new brand called Intelligent Movement to deliver ...
Latest News
Boutique fitness chain 1Rebel opens the doors to its tenth club today (Monday 27 June ...
Latest News
A new report by Deloitte, outlining the social and economic value of the global health ...
Latest News
Barry’s has entered the world of retail, opening a studio in the new Flannels flagship ...
Latest News
The London 2012 Olympic legacy investment designed to improve physical education at primary schools has ...
Featured supplier news
Featured supplier news: How wearables-driven gamification will boost your business
It’s a known fact that gamification is an effective method to make everyday activities and work more fun.
Featured supplier news
Featured supplier news: EGYM announces integration with software provider Fisikal
EGYM has announced an integration with a leading UK-based software company Fisikal to enhance its capabilities to serve the needs of enterprise customers running multi-site operations.
Featured operator news
Featured operator news: Everyone Active to launch new exercise classes to reduce gender gap
As part of their work to break down the barriers that deter women and girls from participating in sport and physical activity, Everyone Active has teamed up with EMD UK to launch new exercise classes linked to the This Girl Can campaign.
Featured operator news
Featured operator news: New £42m Moorways Sports Village to open on 21 May
Everyone Active will open Moorways Sports Village to the public on Saturday 21 May with a grand opening weekend – in time for the half term holidays.
Video Gallery
Total Vibration Solutions / Floors 4 Gyms / TVS Sports Surfaces
Mindbody, Inc
Sport Alliance GmbH
Company profiles
Company profile: Future Fit
More than just a training provider, we offer a range of ready to go and ...
Company profiles
Company profile: Technogym UK Ltd
Technogym offers a complete ecosystem of connected smart equipment, digital services, on-demand training experiences and ...
Supplier Showcases
Supplier showcase - Pulse Fitness: trusted partner
Catalogue Gallery
Click on a catalogue to view it online
Directory
Fitness equipment
A Panatta Sport Srl: Fitness equipment
Flooring
Total Vibration Solutions / TVS Sports Surfaces: Flooring
Wearable technology solutions
MyZone: Wearable technology solutions
Architects/designers
Zynk Design Consultants: Architects/designers
Spa software
SpaBooker: Spa software
On demand
Fitness On Demand: On demand
Skincare
Comfort Zone - Davines S.p.A: Skincare
Salt therapy products
Himalayan Source: Salt therapy products
Whole body cryotherapy
Art of Cryo: Whole body cryotherapy
Lockers/interior design
Crown Sports Lockers: Lockers/interior design
Property & Tenders
Pendine Sands, Carmarthenshire
Carmarthenshire County Council
Property & Tenders
Runcorn
Halton Borough Council
Property & Tenders
Diary dates
12-13 Sep 2022
Wyndham Lake Buena Vista Disney Springs® Resort, Lake Buena Vista, United States
Diary dates
21-21 Sep 2022
Various, London, United Kingdom
Diary dates
25-28 Oct 2022
Messe Stuttgart, Germany
Diary dates
25-28 Oct 2022
Ibiza, Ibiza, Spain
Diary dates
01-07 Dec 2022
tbc, Dunedin, New Zealand
Diary dates
17-18 Mar 2023
Tobacco Dock, London, United Kingdom
Diary dates
Search news, features & products:
Find a supplier:
Les Mills International
Les Mills International
Partner sites