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UNITING THE WORLD OF FITNESS
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Health Club Management

Health Club Management

News

Mayo Clinic study unlocks new anti-ageing science

New science has revealed a potential solution to age-related diseases which works on a systemic basis, improving overall health and reducing the need to treat individual, age-related ailments.

A human trial in the field of senolytics – medicines which remove aged, toxic cells from our bodies – has found these treatments can decrease and potentially eliminate the presence of senescent cells in the body.

These cells are responsible for fuelling age-related diseases, as they've ceased to divide and go on to accumulate in the body, eventually becoming harmful to the tissues around them.

Cells with senescent properties are linked to the occurrence of age-related diseases and have been found in the affected tissues of people with Alzheimer’s, pulmonary fibrosis and osteoarthritis. Senescent cells are also found in people suffering from obesity.

The trial, published by The Lancet in the EBioMedicine Journal on September 18th, was conducted at the Mayo Clinic in Minnesota.

During the study, nine subjects, aged between 50-80 years and receiving diabetes therapy, were administered with senolytic drugs for three days.

Scientists concluded that ‘interventions (in this instance, the administration of senolytic drugs) targeting fundamental ageing processes such as cellular senescence could delay, prevent, or alleviate multiple age-related diseases’ in humans.

The trial findings represent hope for a future systemic solution to ageing and age-related diseases, instead of treating singular diseases one-by-one.

The research was conducted by a team led by James Kirkland, MD, PhD, with Nathan LeBrasseur, PhD, MS, and Tamara Tchkonia, PhD, who all collaborate with the Mayo Clinic.

Other recent research proved that Fisetin, a fruit-based flavonoid, is a potent senolytic which can extend health and lifespan. The substance is found in strawberries, apples, grapes and kiwi fruit.

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Elodie Garamond

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We now have eight sites and offer retreats, such as a retreat in a Moroccan palace and a French chateaux-based yin yoga and writing retreat
People
Our first trial was in a beer fridge, the second was in an ice factory in Pennsylvania. And after seeing first hand the impact that cooler temperatures made on the fitness experience, we both realized that we were truly onto something much bigger than what we had anticipated - Johnny Adamic, co-founder of Brrrn
People
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Ben Gotting & Dave Thomas

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Because of our strong focus on community and inclusivity our members really do range from unemployed, and even homeless, to CEOs and board members of major institutions and celebrities
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News

Mayo Clinic study unlocks new anti-ageing science

New science has revealed a potential solution to age-related diseases which works on a systemic basis, improving overall health and reducing the need to treat individual, age-related ailments.

A human trial in the field of senolytics – medicines which remove aged, toxic cells from our bodies – has found these treatments can decrease and potentially eliminate the presence of senescent cells in the body.

These cells are responsible for fuelling age-related diseases, as they've ceased to divide and go on to accumulate in the body, eventually becoming harmful to the tissues around them.

Cells with senescent properties are linked to the occurrence of age-related diseases and have been found in the affected tissues of people with Alzheimer’s, pulmonary fibrosis and osteoarthritis. Senescent cells are also found in people suffering from obesity.

The trial, published by The Lancet in the EBioMedicine Journal on September 18th, was conducted at the Mayo Clinic in Minnesota.

During the study, nine subjects, aged between 50-80 years and receiving diabetes therapy, were administered with senolytic drugs for three days.

Scientists concluded that ‘interventions (in this instance, the administration of senolytic drugs) targeting fundamental ageing processes such as cellular senescence could delay, prevent, or alleviate multiple age-related diseases’ in humans.

The trial findings represent hope for a future systemic solution to ageing and age-related diseases, instead of treating singular diseases one-by-one.

The research was conducted by a team led by James Kirkland, MD, PhD, with Nathan LeBrasseur, PhD, MS, and Tamara Tchkonia, PhD, who all collaborate with the Mayo Clinic.

Other recent research proved that Fisetin, a fruit-based flavonoid, is a potent senolytic which can extend health and lifespan. The substance is found in strawberries, apples, grapes and kiwi fruit.

Sign up for FREE ezines & magazines
Related news

Mayo Clinic study: HIIT has 'anti-ageing benefits'

28 Jun 2019
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News

Real estate developers are increasingly looking to tap into the "great opportunities" being offered by
The outgoing chief medical officer, professor Dame Sally Davies, has called for urgent action across
A health and wellbeing club which combines exercise and physical activity classes with mental and
VivaFit has entered the Spanish fitness market with the opening of a studio in capital
John Treharne, founder of The Gym Group, has been appointed chair of boutique fitness brand
Parkwood Leisure has launched a programme of workshops, aimed at making its staff more aware
ukactive
ukactive
Physical Company, a specialist equipment supplier based in the UK, has celebrated its thirtieth anniversary.
Be Military Fit (BMF) is planning to diversify its offer – and then expand globally
The company behind a health club concept designed to "transform Saudi Arabia's fitness sector" has
EMD UK, the national governing body for group exercise, has appointed Marcus Kingwell, the current
A major nation-wide campaign is aiming to help people build simple changes into their daily
Regular weekly exercise sessions could delay brain deterioration in people at high risk for Alzheimer's
Lighting design studio Cactus has partnered with cardio climbing gym operator Rise Nation to create
Dyaco International
Dyaco International
The design and construction of a group fitness or exercise studio can have a big
Orangetheory Fitness has opened its 100th franchised site in Canada, seven years after it first
Wearable tech giant Fitbit is partnering with FibriCheck, a health screening and monitoring app, to
The Royal Life Saving Society UK (RLSS UK) has confirmed it is extending its partnership
Optimum Nutrition
Optimum Nutrition
1 - 15 of 11,108
Features
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Now in its eighth year, Myzone has established itself as a key player in the fitness industry. We chat to Myzone's global marketing director, Gemma Bonnett-Kolakowska, about how the brand continues to develop and evolve
Features
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People
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Elodie Garamond

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We now have eight sites and offer retreats, such as a retreat in a Moroccan palace and a French chateaux-based yin yoga and writing retreat
People
Our first trial was in a beer fridge, the second was in an ice factory in Pennsylvania. And after seeing first hand the impact that cooler temperatures made on the fitness experience, we both realized that we were truly onto something much bigger than what we had anticipated - Johnny Adamic, co-founder of Brrrn
People
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Ben Gotting & Dave Thomas

The Foundry: co-founders
Because of our strong focus on community and inclusivity our members really do range from unemployed, and even homeless, to CEOs and board members of major institutions and celebrities
People
WE11 is a disruptive model and is going to cause mayhem in the industry: we’ve flipped the script and given the PTs a fair deal, instead of rinsing them
People
Rather than just being an outdoor fitness company, we felt we could evolve and adapt the business to become a dominating force in fitness generally
People
Our industry starts and ends with people, so I spent my first three weeks visiting our clubs and listening
People
HCM people

Martin Seibold

CEO Life Fit Group
Gathering existing, strong brands under one roof to create the new Life Fit Group made perfect sense
People
HCM people

Rich Hutson

CEO of CHi Fitness and Co-founder of Fire Fitness
The business wasn’t getting the numbers needed, so I raised the prices by 25 per cent. It worked and we didn’t skip a beat
People
The Life Fitness entrepreneur and ALS charity fundraiser is returning to the business that made his name
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Job search
POST YOUR JOB
Featured supplier news
Featured supplier: Gympass brings together corporate workforces and leisure operators
The Gympass mission is to defeat inactivity – a vision shared by many in the leisure industry.
Featured supplier news
Featured supplier: Eleiko makes deadlifting more accessible with the Öppen Deadlift Bar
Eleiko, a Swedish weightlifting equipment specialist, is reinforcing its position in the strength and fitness market with the launch of the Öppen Deadlift Bar,
Company profiles
Company profile: Focus Training
Focus Training is a leading provider of Active IQ and YMCA Awards certified Personal Trainer ...
Company profiles
Company profile: Balanced Body®
Stocked in the UK for fast, costeffective delivery, Balanced Body® delivers versatile and space-saving mind-body ...
Catalogue Gallery
Click on a catalogue to view it online
Directory
Fitness equipment
Stages Cycling: Fitness equipment
Locking solutions
Ojmar: Locking solutions
Spa software
SpaBooker: Spa software
Wearable technology solutions
MyZone: Wearable technology solutions
Audio visual
Hutchison Technologies: Audio visual
Management software
Fisikal: Management software
Governing body
EMD UK: Governing body
Hydrotherapy / spa fragrances
Kemitron GmbH: Hydrotherapy / spa fragrances
Trade associations
International SPA Association - iSPA: Trade associations
Whole body cryotherapy
Zimmer MedizinSysteme GmbH / icelab: Whole body cryotherapy
Property & Tenders
Kirklees Active Leisure
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Diary dates
15 Oct 2019
Loughborough University, Loughborough, United Kingdom
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Diary dates
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tbc, Pinggu, China
Diary dates
17-18 Jun 2020
ExCeL London, London, United Kingdom
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