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UNITING THE WORLD OF FITNESS
Health Club Management

Health Club Management

features

HCM People: Professor Zhen Yandirector of the Center for Skeletal Muscle Research, University of Virginia

Regular exercise may help people survive COVID-19

Published in Health Club Management 2020 issue 4
Zhen Yan set out to show the physiological impact of exercise on COVID-19 outcomes
Zhen Yan set out to show the physiological impact of exercise on COVID-19 outcomes

Approximately 80 per cent of confirmed COVID-19 patients have mild symptoms, make a good recovery and don’t need respiratory support, while others become extremely unwell and need life support. Professor Zhen Yan at the University of Virginia set out to find out why outcomes are so mixed.

Yan found regular exercise may reduce the risk of complications in people with COVID-19, as well as offering the potential for alternative treatment approaches going forward.

He studied an antioxidant called extracellular superoxide dismutase (EcSOD) that’s released by the muscles and into the bloodstream during exercise.

His work “strongly supports” the possibility that higher levels of EcSOD in the body can prevent or at least reduce the severity of acute respiratory distress syndrome (ARDS) – one of the worst outcomes of the COVID-19 virus.

EcSOD does this by hunting down free radicals, binding to organs and protecting tissues from attack by the virus.

“Our findings strongly support that enhanced EcSOD expression from skeletal muscle…which can be redistributed to lung tissue, could be a viable preventative and therapeutic measure in reducing the risk and severity of ARDS in COVID-19 patients,” he said.

Research suggests that even a single session of exercise increases the production of the antioxidant, prompting Yan to urge people to find ways to exercise, even while maintaining social distancing.

Cardiovascular exercise is thought to drive the highest immediate levels of EcSOD production, however, strength training increases muscle mass, meaning it also plays a part in the equation.

Between three and 17 per cent of people with COVID-19 patients will develop ARDS – this percentage goes up once people are hospitalised to between 20 and 42 per cent, as the more extreme cases succumb to the virus.

“We often say that exercise is medicine. This insight into the role of EcSOD in the body is a perfect example of how we can learn from the biological process of exercise to advance medicine,” Yan said.

“While we strive to learn more about the mysteries of the superb benefits of regular exercise, we don’t have to wait until we know everything before starting to take advantage of this benefit.”

Yan said EcSOD may also prevent multi-organ dysfunction syndrome – in which multiple organs begin to fail.

The antioxidant is also being proposed as a potential therapy for diabetic retinopathy, a complication of diabetes that can lead to blindness.

Low levels of EcSOD are seen in heart disease, kidney failure and osteoarthritis.

Find out more: faculty.virginia.edu/yanlab

Sign up here to get HCM's weekly ezine and every issue of HCM magazine free on digital.
Strength training grows muscle mass, increasing the potential for secreting EcSOD
Strength training grows muscle mass, increasing the potential for secreting EcSOD
https://www.leisureopportunities.co.uk/images/2020/945024_195781.jpg
Regular exercise may reduce the risk of complications in people with COVID-19
Professor Zhen Yan, Center for Skeletal Muscle Research, University of Virginia, covid-19,coronavirus,
HCM magazine
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Diary dates
13-14 Oct 2021
Online,
Diary dates
01-03 Feb 2022
Coventry Building Society Arena, Coventry, United Kingdom
Diary dates
07-10 Apr 2022
Exhibition Centre , Cologne, Germany
Diary dates
15-16 Jun 2022
ExCeL London, London, United Kingdom
Diary dates
01-07 Dec 2022
tbc, Dunedin, New Zealand
Diary dates

features

HCM People: Professor Zhen Yandirector of the Center for Skeletal Muscle Research, University of Virginia

Regular exercise may help people survive COVID-19

Published in Health Club Management 2020 issue 4
Zhen Yan set out to show the physiological impact of exercise on COVID-19 outcomes
Zhen Yan set out to show the physiological impact of exercise on COVID-19 outcomes

Approximately 80 per cent of confirmed COVID-19 patients have mild symptoms, make a good recovery and don’t need respiratory support, while others become extremely unwell and need life support. Professor Zhen Yan at the University of Virginia set out to find out why outcomes are so mixed.

Yan found regular exercise may reduce the risk of complications in people with COVID-19, as well as offering the potential for alternative treatment approaches going forward.

He studied an antioxidant called extracellular superoxide dismutase (EcSOD) that’s released by the muscles and into the bloodstream during exercise.

His work “strongly supports” the possibility that higher levels of EcSOD in the body can prevent or at least reduce the severity of acute respiratory distress syndrome (ARDS) – one of the worst outcomes of the COVID-19 virus.

EcSOD does this by hunting down free radicals, binding to organs and protecting tissues from attack by the virus.

“Our findings strongly support that enhanced EcSOD expression from skeletal muscle…which can be redistributed to lung tissue, could be a viable preventative and therapeutic measure in reducing the risk and severity of ARDS in COVID-19 patients,” he said.

Research suggests that even a single session of exercise increases the production of the antioxidant, prompting Yan to urge people to find ways to exercise, even while maintaining social distancing.

Cardiovascular exercise is thought to drive the highest immediate levels of EcSOD production, however, strength training increases muscle mass, meaning it also plays a part in the equation.

Between three and 17 per cent of people with COVID-19 patients will develop ARDS – this percentage goes up once people are hospitalised to between 20 and 42 per cent, as the more extreme cases succumb to the virus.

“We often say that exercise is medicine. This insight into the role of EcSOD in the body is a perfect example of how we can learn from the biological process of exercise to advance medicine,” Yan said.

“While we strive to learn more about the mysteries of the superb benefits of regular exercise, we don’t have to wait until we know everything before starting to take advantage of this benefit.”

Yan said EcSOD may also prevent multi-organ dysfunction syndrome – in which multiple organs begin to fail.

The antioxidant is also being proposed as a potential therapy for diabetic retinopathy, a complication of diabetes that can lead to blindness.

Low levels of EcSOD are seen in heart disease, kidney failure and osteoarthritis.

Find out more: faculty.virginia.edu/yanlab

Sign up here to get HCM's weekly ezine and every issue of HCM magazine free on digital.
Strength training grows muscle mass, increasing the potential for secreting EcSOD
Strength training grows muscle mass, increasing the potential for secreting EcSOD
https://www.leisureopportunities.co.uk/images/2020/945024_195781.jpg
Regular exercise may reduce the risk of complications in people with COVID-19
Professor Zhen Yan, Center for Skeletal Muscle Research, University of Virginia, covid-19,coronavirus,
Latest News
Boxing-inspired fitness operator Rumble has signed a master franchise agreement in Australia, which could see ...
Latest News
Hotel giant Accor has launched a new bespoke, premium fitness service for its upmarket Pullman ...
Latest News
People should concentrate on exercise and staying fit – rather than dieting and weight loss ...
Latest News
Sibec Europe, scheduled to take place in Cologne, Germany, from 2 to 5 November 2021, ...
Latest News
Swim England has warned that 2,000 swimming pools could be lost forever unless the government ...
Latest News
Sports Minister, Nigel Huddleston, has joined gym-goers this morning to kick-off the annual National Fitness ...
Latest News
A new high-end workspace, designed for the use of personal trainers, coaches and other health ...
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VAT reform, adjustments in business rates and a fitness-led high street regeneration push could see ...
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Featured supplier news
Featured supplier news: Technogym awarded “Supplier of the year” at ukactive awards 2021
The best in class of the physical activity sector have been revealed at the ukactive Awards 2021.
Featured supplier news
Featured supplier news: Shipping gym equipment from Europe to the UK
Despite the Prime Minister’s claims that trade with the EU would be tariff-free post-Brexit, the reality has become very different when importing gym equipment from the EU.
Featured operator news
Featured operator news: Everyone Active generates £342m in social value
Award-winning leisure operator Everyone Active generated £342million in social value at its sites across the country in 2019/20.
Featured operator news
Featured operator news: Being active helps Parkwood Leisure customers save the NHS £16m
Parkwood Leisure, one of the UK’s leading public leisure facilities operators, helped prevent more than 7,000 cases of stroke, dementia, depression and type 2 diabetes in 2019, saving the NHS £16 million, a new social value report has shown.
Company profiles
Company profile: Mediana Co., Ltd.
Mediana specialises in the manufacture of medical and health care devices, such as body composition ...
Company profiles
Company profile: Xn Leisure Systems Ltd
Xn Leisure is a provider of cutting-edge health and fitness software, offering an exceptional service ...
Catalogue Gallery
Click on a catalogue to view it online
Directory
Red Light Therapy
 Red Light Rising: Red Light Therapy
Spa software
SpaBooker: Spa software
Wearable technology solutions
MyZone: Wearable technology solutions
Management software
Premier Software Solutions: Management software
Skincare
Sothys: Skincare
Fitness equipment
Precor: Fitness equipment
Architects/designers
Zynk Design Consultants: Architects/designers
Hydrotherapy / spa fragrances
Kemitron GmbH: Hydrotherapy / spa fragrances
Salt therapy products
Himalayan Source: Salt therapy products
Uniforms
Service Sport: Uniforms
Property & Tenders
Welwyn Garden City
Welwyn Hatfield Borough Council
Property & Tenders
Newport, Shropshire
Lilleshall Sports Academy
Property & Tenders
Diary dates
13-14 Oct 2021
Online,
Diary dates
01-03 Feb 2022
Coventry Building Society Arena, Coventry, United Kingdom
Diary dates
07-10 Apr 2022
Exhibition Centre , Cologne, Germany
Diary dates
15-16 Jun 2022
ExCeL London, London, United Kingdom
Diary dates
01-07 Dec 2022
tbc, Dunedin, New Zealand
Diary dates
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