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FreeMotion Fitness
FreeMotion Fitness
FreeMotion Fitness
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UNITING THE WORLD OF FITNESS
Health Club Management

Health Club Management

News

Mayo Clinic study unlocks new anti-ageing science

New science has revealed a potential solution to age-related diseases which works on a systemic basis, improving overall health and reducing the need to treat individual, age-related ailments.

A human trial in the field of senolytics – medicines which remove aged, toxic cells from our bodies – has found these treatments can decrease and potentially eliminate the presence of senescent cells in the body.

These cells are responsible for fuelling age-related diseases, as they've ceased to divide and go on to accumulate in the body, eventually becoming harmful to the tissues around them.

Cells with senescent properties are linked to the occurrence of age-related diseases and have been found in the affected tissues of people with Alzheimer’s, pulmonary fibrosis and osteoarthritis. Senescent cells are also found in people suffering from obesity.

The trial, published by The Lancet in the EBioMedicine Journal on September 18th, was conducted at the Mayo Clinic in Minnesota.

During the study, nine subjects, aged between 50-80 years and receiving diabetes therapy, were administered with senolytic drugs for three days.

Scientists concluded that ‘interventions (in this instance, the administration of senolytic drugs) targeting fundamental ageing processes such as cellular senescence could delay, prevent, or alleviate multiple age-related diseases’ in humans.

The trial findings represent hope for a future systemic solution to ageing and age-related diseases, instead of treating singular diseases one-by-one.

The research was conducted by a team led by James Kirkland, MD, PhD, with Nathan LeBrasseur, PhD, MS, and Tamara Tchkonia, PhD, who all collaborate with the Mayo Clinic.

Other recent research proved that Fisetin, a fruit-based flavonoid, is a potent senolytic which can extend health and lifespan. The substance is found in strawberries, apples, grapes and kiwi fruit.

Sign up here to get HCM's weekly ezine and every issue of HCM magazine free on digital.
New science has revealed a potential solution to age-related diseases which works on a systemic basis, improving overall health and reducing the need to treat individual, age- related ailments.
HAF,SAB,CPW,CAS,ACD,RES
imagesX/THUMB343085_858444_482128.jpg
Latest News
Xponential Fitness has acquired Body Fit Training in a deal worth US$44m. The deal takes ...
Latest News
Exercise has been highlighted as a crucial weapon in cancer patients’ battle against the disease. ...
Latest News
The global health and fitness industry is returning to a busy programme of live trade ...
Latest News
Matrix and Intelivideo have signed a strategic partnership, which will see Intelivideo's fitness content integrated ...
Latest News
Nadine Dorries, the recently appointed secretary of state for digital, culture, media and sport at ...
Latest News
Mindbody has announced it's buying ClassPass, the consumer wellness subscription service that enables people to ...
Latest News
Tanni Grey-Thompson has outlined her vision on how the physical activity sector can play "the ...
Latest News
The Global Health & Fitness Alliance (GHFA) has revealed the makeup of its inaugural nine-member ...
HCM Magazine
Sponsored
Fitness professionals make great social prescribing linkworkers, as their consultation skills, ability to recognise cues when speaking to people and follow-up on actions are all called upon
HCM Magazine
Everyone’s talking about
Booming membership sales, busy suburban clubs and members visiting during the working day. Operators are reporting it’s good to be back. Kath Hudson finds out what business has been like since the re-set button was pressed
HCM Magazine
Policy
Generations rarely have the opportunity to reset public opinion and effect behaviour change for good, but post-pandemic two unequal movements with a lot in common will be the focus of governments, says David Minton
HCM Magazine
Supplier launch
Life Fitness introduces Integrity SL, the next-generation LED console with intuitive functionality and digital connectivity
HCM Magazine
Editor's letter
The appetite for health clubs is strong among consumers and investors – to take advantage of this, operators must figure out how to meet key challenges in operationally sustainable ways
HCM Magazine
Sponsored
Billed as the ‘2021 Experience Tour’, Egym has taken its connected gym floor experience on the road around the UK
HCM Magazine
Sponsored
Les Mills is launching a new digital network called Les Mills Connect to help clubs build back better and emerge from the pandemic with a stronger business
HCM Magazine
HCM magazine
David Minton says the healthy movement industry is ten times bigger than the health club sector, and the care industry four times bigger and ask why we’re not rushing to collaborate?
HCM magazine
Our competition need to fasten their seatbelts
HCM magazine
Screens display power generated from each piece of equipment, allowing people to compete against each other for kilowatt hours produced
Featured supplier news
Featured supplier news: FitnessOnDemand launches new live-streaming feature for all fitness clubs and their members
FitnessOnDemand (FOD) [IHRSA BOOTH 1509] the leader in on-demand content from the world’s most innovative fitness brands and celebrity trainers, this month introduces a new platform evolution for all club operators and their customers.
Featured supplier news
Featured supplier news: Humanising the member app experience
FunXtion has upgraded its White Label Member App with a raft of new features to support its partners in scaling up and keeping up with rising member expectations.
Featured operator news
Featured operator news: Everyone Active bolsters Everyone on Demand and enters second year with five new partnerships
Everyone Active has signed a number of new deals which will see the operator strengthen its digital product offering, Everyone on Demand.
Featured operator news
Featured operator news: Everyone Active generates £342m in social value
Award-winning leisure operator Everyone Active generated £342million in social value at its sites across the country in 2019/20.
Company profiles
Company profile: ServiceSport (UK) Ltd
ServiceSport (UK) Ltd specialises in maintaining, servicing and re-manufacturing all brands of cardiovascular and resistance ...
Company profiles
Company profile: FIBO Global Fitness
FIBO Global Fitness is the leading international trade show for fitness, wellness & health....
Catalogue Gallery
Click on a catalogue to view it online
Directory
Whole body cryotherapy
Zimmer MedizinSysteme GmbH / icelab: Whole body cryotherapy
Salt therapy products
Saltability: Salt therapy products
trade associations
International SPA Association - iSPA: trade associations
Skincare
Comfort Zone - Davines S.p.A: Skincare
Exercise equipment
Power Plate: Exercise equipment
Uniforms
Service Sport: Uniforms
Fitness equipment
Precor: Fitness equipment
Wearable technology solutions
MyZone: Wearable technology solutions
Independent service & maintenance
Servicesport UK Limited: Independent service & maintenance
Architects/designers
Zynk Design Consultants: Architects/designers
Property & Tenders
Welwyn Garden City
Welwyn Hatfield Borough Council
Property & Tenders
Newport, Shropshire
Lilleshall Sports Academy
Property & Tenders
Diary dates
01-03 Feb 2022
Coventry Building Society Arena, Coventry, United Kingdom
Diary dates
07-10 Apr 2022
Exhibition Centre , Cologne, Germany
Diary dates
15-16 Jun 2022
ExCeL London, London, United Kingdom
Diary dates
01-07 Dec 2022
tbc, Dunedin, New Zealand
Diary dates

News

Mayo Clinic study unlocks new anti-ageing science

New science has revealed a potential solution to age-related diseases which works on a systemic basis, improving overall health and reducing the need to treat individual, age-related ailments.

A human trial in the field of senolytics – medicines which remove aged, toxic cells from our bodies – has found these treatments can decrease and potentially eliminate the presence of senescent cells in the body.

These cells are responsible for fuelling age-related diseases, as they've ceased to divide and go on to accumulate in the body, eventually becoming harmful to the tissues around them.

Cells with senescent properties are linked to the occurrence of age-related diseases and have been found in the affected tissues of people with Alzheimer’s, pulmonary fibrosis and osteoarthritis. Senescent cells are also found in people suffering from obesity.

The trial, published by The Lancet in the EBioMedicine Journal on September 18th, was conducted at the Mayo Clinic in Minnesota.

During the study, nine subjects, aged between 50-80 years and receiving diabetes therapy, were administered with senolytic drugs for three days.

Scientists concluded that ‘interventions (in this instance, the administration of senolytic drugs) targeting fundamental ageing processes such as cellular senescence could delay, prevent, or alleviate multiple age-related diseases’ in humans.

The trial findings represent hope for a future systemic solution to ageing and age-related diseases, instead of treating singular diseases one-by-one.

The research was conducted by a team led by James Kirkland, MD, PhD, with Nathan LeBrasseur, PhD, MS, and Tamara Tchkonia, PhD, who all collaborate with the Mayo Clinic.

Other recent research proved that Fisetin, a fruit-based flavonoid, is a potent senolytic which can extend health and lifespan. The substance is found in strawberries, apples, grapes and kiwi fruit.

Sign up here to get HCM's weekly ezine and every issue of HCM magazine free on digital.
New science has revealed a potential solution to age-related diseases which works on a systemic basis, improving overall health and reducing the need to treat individual, age- related ailments.
HAF,SAB,CPW,CAS,ACD,RES
imagesX/THUMB343085_858444_482128.jpg

News

Xponential Fitness has acquired Body Fit Training in a deal worth US$44m. The deal takes
Exercise has been highlighted as a crucial weapon in cancer patients’ battle against the disease.
The global health and fitness industry is returning to a busy programme of live trade
Matrix and Intelivideo have signed a strategic partnership, which will see Intelivideo's fitness content integrated
Nadine Dorries, the recently appointed secretary of state for digital, culture, media and sport at
Mindbody has announced it's buying ClassPass, the consumer wellness subscription service that enables people to
Les Mills
Les Mills
FunXtion has upgraded its White Label Member App with a raft of new features to
Tanni Grey-Thompson has outlined her vision on how the physical activity sector can play "the
The Global Health & Fitness Alliance (GHFA) has revealed the makeup of its inaugural nine-member
The 40th Annual IHRSA International Convention & Trade Show (IHRSA 2021) begins today in Dallas,
A new study has suggested that strength training can result in people losing around a
Basic-Fit has officially opened its 1,000th club, with the launch of a new site in
Health club operator Life Time Group has become a publicly traded company again, after it
Miha Bodytec GmbH
Miha Bodytec GmbH
Matt Miller, founder of leading yoga training platform Broga has announced the launch of Earth+Sky
Creating workout experiences will be the main theme of this year's Retention Convention, which will
Marg Mayne will stand down as CEO of Mytime Active next year, after more than
French car manufacturer Citroën and hotel brand Pullman Hotels & Resorts have partnered to create
Les Mills is expanding its digital operations by replacing its existing on-demand services with the
Sport England has spent £1.5m launching its own on-demand fitness platform, with the hope of
New research by Barclays Corporate Banking reveals that the leisure, fitness, spa and hospitality industries
FreeMotion Fitness
FreeMotion Fitness
CEO of Orbit4, Daniel Jones, says: “There’s no reason traditional gyms and smart gyms can’t
Tanni Grey-Thompson has announced she will hand over her role as ukactive chair in August
A group of leading health and fitness companies in Romania have joined forces to launch
FIBO Exhibition
FIBO Exhibition
1 - 20 of 12,048
HCM Magazine
Sponsored
Fitness professionals make great social prescribing linkworkers, as their consultation skills, ability to recognise cues when speaking to people and follow-up on actions are all called upon
HCM Magazine
Everyone’s talking about
Booming membership sales, busy suburban clubs and members visiting during the working day. Operators are reporting it’s good to be back. Kath Hudson finds out what business has been like since the re-set button was pressed
HCM Magazine
Policy
Generations rarely have the opportunity to reset public opinion and effect behaviour change for good, but post-pandemic two unequal movements with a lot in common will be the focus of governments, says David Minton
HCM Magazine
Supplier launch
Life Fitness introduces Integrity SL, the next-generation LED console with intuitive functionality and digital connectivity
HCM Magazine
Editor's letter
The appetite for health clubs is strong among consumers and investors – to take advantage of this, operators must figure out how to meet key challenges in operationally sustainable ways
HCM Magazine
Sponsored
Billed as the ‘2021 Experience Tour’, Egym has taken its connected gym floor experience on the road around the UK
HCM Magazine
Sponsored
Les Mills is launching a new digital network called Les Mills Connect to help clubs build back better and emerge from the pandemic with a stronger business
HCM Magazine
HCM magazine
David Minton says the healthy movement industry is ten times bigger than the health club sector, and the care industry four times bigger and ask why we’re not rushing to collaborate?
HCM magazine
Our competition need to fasten their seatbelts
HCM magazine
Screens display power generated from each piece of equipment, allowing people to compete against each other for kilowatt hours produced
HCM magazine
HCM People

Danielle Obe

Chair, The Black Swimming Association
Our vision is a future with ethnic diversity in aquatics
HCM magazine
In this issue, we’re focusing on sharing insights and thought leadership to highlight opportunities for the development of the sector in terms of both markets and offerings
HCM magazine
Our equipment doesn't consume power but does generate it, recycling human energy
HCM magazine
Fuel the debate about issues and opportunities across the industry. We’d love to hear from you – [email protected]
HCM magazine
HCM people

David Beckham

Global partner, F45
This partnership with F45 is an exciting business venture for me
HCM magazine
HCM People

Colin Waggett

CEO, Third Space
We first started talking to KSL over two years ago, so this was not a rushed partnership
HCM magazine
Featured supplier news
Featured supplier news: FitnessOnDemand launches new live-streaming feature for all fitness clubs and their members
FitnessOnDemand (FOD) [IHRSA BOOTH 1509] the leader in on-demand content from the world’s most innovative fitness brands and celebrity trainers, this month introduces a new platform evolution for all club operators and their customers.
Featured supplier news
Featured supplier news: Humanising the member app experience
FunXtion has upgraded its White Label Member App with a raft of new features to support its partners in scaling up and keeping up with rising member expectations.
Featured operator news
Featured operator news: Everyone Active bolsters Everyone on Demand and enters second year with five new partnerships
Everyone Active has signed a number of new deals which will see the operator strengthen its digital product offering, Everyone on Demand.
Featured operator news
Featured operator news: Everyone Active generates £342m in social value
Award-winning leisure operator Everyone Active generated £342million in social value at its sites across the country in 2019/20.
Company profiles
Company profile: ServiceSport (UK) Ltd
ServiceSport (UK) Ltd specialises in maintaining, servicing and re-manufacturing all brands of cardiovascular and resistance ...
Company profiles
Company profile: FIBO Global Fitness
FIBO Global Fitness is the leading international trade show for fitness, wellness & health....
Catalogue Gallery
Click on a catalogue to view it online
Directory
Whole body cryotherapy
Zimmer MedizinSysteme GmbH / icelab: Whole body cryotherapy
Salt therapy products
Saltability: Salt therapy products
trade associations
International SPA Association - iSPA: trade associations
Skincare
Comfort Zone - Davines S.p.A: Skincare
Exercise equipment
Power Plate: Exercise equipment
Uniforms
Service Sport: Uniforms
Fitness equipment
Precor: Fitness equipment
Wearable technology solutions
MyZone: Wearable technology solutions
Independent service & maintenance
Servicesport UK Limited: Independent service & maintenance
Architects/designers
Zynk Design Consultants: Architects/designers
Property & Tenders
Welwyn Garden City
Welwyn Hatfield Borough Council
Property & Tenders
Newport, Shropshire
Lilleshall Sports Academy
Property & Tenders
Diary dates
01-03 Feb 2022
Coventry Building Society Arena, Coventry, United Kingdom
Diary dates
07-10 Apr 2022
Exhibition Centre , Cologne, Germany
Diary dates
15-16 Jun 2022
ExCeL London, London, United Kingdom
Diary dates
01-07 Dec 2022
tbc, Dunedin, New Zealand
Diary dates
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FreeMotion Fitness
FreeMotion Fitness