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Les Mills International
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UNITING THE WORLD OF FITNESS
Health Club Management

Health Club Management

features

HCM People: Professor Zhen Yandirector of the Center for Skeletal Muscle Research, University of Virginia

Regular exercise may help people survive COVID-19

Published in Health Club Management 2020 issue 4
Zhen Yan set out to show the physiological impact of exercise on COVID-19 outcomes
Zhen Yan set out to show the physiological impact of exercise on COVID-19 outcomes

Approximately 80 per cent of confirmed COVID-19 patients have mild symptoms, make a good recovery and don’t need respiratory support, while others become extremely unwell and need life support. Professor Zhen Yan at the University of Virginia set out to find out why outcomes are so mixed.

Yan found regular exercise may reduce the risk of complications in people with COVID-19, as well as offering the potential for alternative treatment approaches going forward.

He studied an antioxidant called extracellular superoxide dismutase (EcSOD) that’s released by the muscles and into the bloodstream during exercise.

His work “strongly supports” the possibility that higher levels of EcSOD in the body can prevent or at least reduce the severity of acute respiratory distress syndrome (ARDS) – one of the worst outcomes of the COVID-19 virus.

EcSOD does this by hunting down free radicals, binding to organs and protecting tissues from attack by the virus.

“Our findings strongly support that enhanced EcSOD expression from skeletal muscle…which can be redistributed to lung tissue, could be a viable preventative and therapeutic measure in reducing the risk and severity of ARDS in COVID-19 patients,” he said.

Research suggests that even a single session of exercise increases the production of the antioxidant, prompting Yan to urge people to find ways to exercise, even while maintaining social distancing.

Cardiovascular exercise is thought to drive the highest immediate levels of EcSOD production, however, strength training increases muscle mass, meaning it also plays a part in the equation.

Between three and 17 per cent of people with COVID-19 patients will develop ARDS – this percentage goes up once people are hospitalised to between 20 and 42 per cent, as the more extreme cases succumb to the virus.

“We often say that exercise is medicine. This insight into the role of EcSOD in the body is a perfect example of how we can learn from the biological process of exercise to advance medicine,” Yan said.

“While we strive to learn more about the mysteries of the superb benefits of regular exercise, we don’t have to wait until we know everything before starting to take advantage of this benefit.”

Yan said EcSOD may also prevent multi-organ dysfunction syndrome – in which multiple organs begin to fail.

The antioxidant is also being proposed as a potential therapy for diabetic retinopathy, a complication of diabetes that can lead to blindness.

Low levels of EcSOD are seen in heart disease, kidney failure and osteoarthritis.

Find out more: faculty.virginia.edu/yanlab

Sign up here to get HCM's weekly ezine and every issue of HCM magazine free on digital.
Strength training grows muscle mass, increasing the potential for secreting EcSOD
Strength training grows muscle mass, increasing the potential for secreting EcSOD
https://www.leisureopportunities.co.uk/images/2020/945024_195781.jpg
Regular exercise may reduce the risk of complications in people with COVID-19
Professor Zhen Yan, Center for Skeletal Muscle Research, University of Virginia, covid-19,coronavirus,
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features

HCM People: Professor Zhen Yandirector of the Center for Skeletal Muscle Research, University of Virginia

Regular exercise may help people survive COVID-19

Published in Health Club Management 2020 issue 4
Zhen Yan set out to show the physiological impact of exercise on COVID-19 outcomes
Zhen Yan set out to show the physiological impact of exercise on COVID-19 outcomes

Approximately 80 per cent of confirmed COVID-19 patients have mild symptoms, make a good recovery and don’t need respiratory support, while others become extremely unwell and need life support. Professor Zhen Yan at the University of Virginia set out to find out why outcomes are so mixed.

Yan found regular exercise may reduce the risk of complications in people with COVID-19, as well as offering the potential for alternative treatment approaches going forward.

He studied an antioxidant called extracellular superoxide dismutase (EcSOD) that’s released by the muscles and into the bloodstream during exercise.

His work “strongly supports” the possibility that higher levels of EcSOD in the body can prevent or at least reduce the severity of acute respiratory distress syndrome (ARDS) – one of the worst outcomes of the COVID-19 virus.

EcSOD does this by hunting down free radicals, binding to organs and protecting tissues from attack by the virus.

“Our findings strongly support that enhanced EcSOD expression from skeletal muscle…which can be redistributed to lung tissue, could be a viable preventative and therapeutic measure in reducing the risk and severity of ARDS in COVID-19 patients,” he said.

Research suggests that even a single session of exercise increases the production of the antioxidant, prompting Yan to urge people to find ways to exercise, even while maintaining social distancing.

Cardiovascular exercise is thought to drive the highest immediate levels of EcSOD production, however, strength training increases muscle mass, meaning it also plays a part in the equation.

Between three and 17 per cent of people with COVID-19 patients will develop ARDS – this percentage goes up once people are hospitalised to between 20 and 42 per cent, as the more extreme cases succumb to the virus.

“We often say that exercise is medicine. This insight into the role of EcSOD in the body is a perfect example of how we can learn from the biological process of exercise to advance medicine,” Yan said.

“While we strive to learn more about the mysteries of the superb benefits of regular exercise, we don’t have to wait until we know everything before starting to take advantage of this benefit.”

Yan said EcSOD may also prevent multi-organ dysfunction syndrome – in which multiple organs begin to fail.

The antioxidant is also being proposed as a potential therapy for diabetic retinopathy, a complication of diabetes that can lead to blindness.

Low levels of EcSOD are seen in heart disease, kidney failure and osteoarthritis.

Find out more: faculty.virginia.edu/yanlab

Sign up here to get HCM's weekly ezine and every issue of HCM magazine free on digital.
Strength training grows muscle mass, increasing the potential for secreting EcSOD
Strength training grows muscle mass, increasing the potential for secreting EcSOD
https://www.leisureopportunities.co.uk/images/2020/945024_195781.jpg
Regular exercise may reduce the risk of complications in people with COVID-19
Professor Zhen Yan, Center for Skeletal Muscle Research, University of Virginia, covid-19,coronavirus,
Latest News
Rainer Schaller, founder of budget gym megabrand McFIT, says that the global fitness industry will ...
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The most high-risk and controversial Olympics of modern times begin today (23 July) in Tokyo, ...
Latest News
Further research into the levels of positive COVID-19 cases among those to have visited fitness ...
Latest News
Planning approval has been granted to what is set to become one of the first ...
Latest News
Digital fitness content provider, Wexer, is launching a new wellness resource on its connected Web ...
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Leisure-net has revealed plans to transform its active-net business event from an annual face-to-face gathering ...
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Featured supplier news: Introducing the Official Hammer Strength Box: a complete small group training solution
With gyms reopening as the fitness industry recovers from the impact of the pandemic, members are seeking social interaction and engaging training experiences in a small group setting.
Featured supplier news
Featured supplier news: FunXtion enhance interactive workouts with the launch of Virtual Player
Digital meets personal with the new Virtual Player from FunXtion, experts in interactive fitness, which allows clubs to stream and schedule world class virtual classes anytime, providing an interactive workout experience on the gym floor, functional area or directly to members at home via an app.
Featured operator news
Featured operator news: Everyone Active generates £342m in social value
Award-winning leisure operator Everyone Active generated £342million in social value at its sites across the country in 2019/20.
Featured operator news
Featured operator news: Everyone Active bolsters Everyone on Demand and enters second year with five new partnerships
Everyone Active has signed a number of new deals which will see the operator strengthen its digital product offering, Everyone on Demand.
Company profiles
Company profile: Zimmer MedizinSysteme GmbH
Imagine a short treatment combined with many positive and long-lasting effects that your customers will ...
Company profiles
Company profile: Jordan Fitness
Jordan Fitness have been at the forefront of premium gym design, with a strong reputation ...
Supplier Showcases
Supplier showcase - Safe Space: Changing concept
Catalogue Gallery
Click on a catalogue to view it online
Directory
Independent service & maintenance
Servicesport UK Limited: Independent service & maintenance
Architects/designers
Zynk Design Consultants: Architects/designers
Spa software
SpaBooker: Spa software
Lockers/interior design
Safe Space Lockers Ltd: Lockers/interior design
Red Light Therapy
 Red Light Rising: Red Light Therapy
Hydrotherapy / spa fragrances
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Diary dates
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Locations worldwide,
Diary dates
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Messe Stuttgart, Germany
Diary dates
13-14 Oct 2021
Online,
Diary dates
04-07 Nov 2021
Exhibition Centre , Cologne, Germany
Diary dates
01-03 Feb 2022
Coventry Building Society Arena, Coventry, United Kingdom
Diary dates
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ExCeL London, London, United Kingdom
Diary dates
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tbc, Dunedin, New Zealand
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Les Mills International
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