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Les Mills International
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UNITING THE WORLD OF FITNESS
Health Club Management

Health Club Management

features

Research: Exercise can counter diabetes damage

Being physically active can heal damage caused by diabetes, enabling the activation of a natural system that grows new blood vessels, according to research in the US

Published in Health Club Management 2022 issue 4
One 45 minute ssession was enough to register a positive impact / Shutterstock/Juice Flair
One 45 minute ssession was enough to register a positive impact / Shutterstock/Juice Flair
Exercise can simulate the growth of new blood vessels when existing ones are ravaged by diabetes

Diabetes not only damages existing blood vessels but also hinders the body’s innate ability to grow new ones in the face of disease and injury.

Scientists at Medical College of Georgia (MCG), however, have found that exercise can help enable angiogenesis – the formation of new blood vessels – which in turn reverses the damage caused by diabetes.

In a study published in The FASEB Journal, a team at MCG’s Vascular Biology Center found the first evidence that in the face of diabetes, even one 45-minute session of moderate-intensity exercise prompts the release of more exosomes into the blood to deliver more of the protein ATP7A directly to cells, which can set angiogenesis in motion. Exosomes are submicroscopic packages filled with biologically active ‘cargo’.

One cardio session
In a sample of healthy 50-something-year-olds, one cardio session increased levels of ATP7A in the exosomes that attached to endothelial cells.

Exercise also increased levels of extracellular superoxide dismutase (SOD3), an important natural antioxidant produced by vascular smooth muscle cells in the walls of blood vessels, as well as skeletal muscle cells, which helps maintain healthy levels of reactive oxygen species or ROS.

ROS is a natural byproduct of our use of oxygen that is an important cell signal, enabling a variety of functions. But in diabetes, high blood sugar levels result in higher ROS levels that instead hinder important normal functions.

Dr Tohru Fukai, MCG vascular biologist and cardiologist and lead author of the study, said: “ATP7A levels are reduced in diabetes and we now have some of the first evidence that exosomes actually impair angiogenesis among those with Type 2 diabetes.

Read the full research report: Exercise improves angiogenic function of circulating exosomes in type 2 diabetes: Role of exosomal SOD3 at www.hcmmag.com/angiogenic

https://www.leisureopportunities.co.uk/images/2022/535084_535875.jpg
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features

Research: Exercise can counter diabetes damage

Being physically active can heal damage caused by diabetes, enabling the activation of a natural system that grows new blood vessels, according to research in the US

Published in Health Club Management 2022 issue 4
One 45 minute ssession was enough to register a positive impact / Shutterstock/Juice Flair
One 45 minute ssession was enough to register a positive impact / Shutterstock/Juice Flair
Exercise can simulate the growth of new blood vessels when existing ones are ravaged by diabetes

Diabetes not only damages existing blood vessels but also hinders the body’s innate ability to grow new ones in the face of disease and injury.

Scientists at Medical College of Georgia (MCG), however, have found that exercise can help enable angiogenesis – the formation of new blood vessels – which in turn reverses the damage caused by diabetes.

In a study published in The FASEB Journal, a team at MCG’s Vascular Biology Center found the first evidence that in the face of diabetes, even one 45-minute session of moderate-intensity exercise prompts the release of more exosomes into the blood to deliver more of the protein ATP7A directly to cells, which can set angiogenesis in motion. Exosomes are submicroscopic packages filled with biologically active ‘cargo’.

One cardio session
In a sample of healthy 50-something-year-olds, one cardio session increased levels of ATP7A in the exosomes that attached to endothelial cells.

Exercise also increased levels of extracellular superoxide dismutase (SOD3), an important natural antioxidant produced by vascular smooth muscle cells in the walls of blood vessels, as well as skeletal muscle cells, which helps maintain healthy levels of reactive oxygen species or ROS.

ROS is a natural byproduct of our use of oxygen that is an important cell signal, enabling a variety of functions. But in diabetes, high blood sugar levels result in higher ROS levels that instead hinder important normal functions.

Dr Tohru Fukai, MCG vascular biologist and cardiologist and lead author of the study, said: “ATP7A levels are reduced in diabetes and we now have some of the first evidence that exosomes actually impair angiogenesis among those with Type 2 diabetes.

Read the full research report: Exercise improves angiogenic function of circulating exosomes in type 2 diabetes: Role of exosomal SOD3 at www.hcmmag.com/angiogenic

https://www.leisureopportunities.co.uk/images/2022/535084_535875.jpg
Exercise can stimulate the growth of new blood vessels when existing ones are ravaged by diabetes, find researchers
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Featured supplier news: Parkwood Leisure celebrates milestone of teaching 100,000 children to swim
Parkwood Leisure, one of the UK’s leading leisure operators, has reached the milestone of teaching 100,000 children to swim through its Learn To Swim Programme.
Featured supplier news
Featured supplier news: How wearables-driven gamification will boost your business
It’s a known fact that gamification is an effective method to make everyday activities and work more fun.
Featured operator news
Featured operator news: Everyone Active to launch new exercise classes to reduce gender gap
As part of their work to break down the barriers that deter women and girls from participating in sport and physical activity, Everyone Active has teamed up with EMD UK to launch new exercise classes linked to the This Girl Can campaign.
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Following a competitive tendering process, Serco Leisure and its partner More Leisure Community Trust Limited (MLCT) have been awarded a 10-year contract by Mansfield District Council to operate three centres in the town, starting 1 May 2022.
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Company profile: EMD UK
EMD UK is the national governing body for group exercise. Funded by Sport England, EMD ...
Company profiles
Company profile: Indigofitness Ltd
We Create Training Spaces! We've been designing and delivering high quality training spaces for almost ...
Catalogue Gallery
Click on a catalogue to view it online
Directory
Lockers/interior design
Safe Space Lockers Ltd: Lockers/interior design
On demand
Fitness On Demand: On demand
Fitness equipment
A Panatta Sport Srl: Fitness equipment
Management software
Premier Software Solutions: Management software
Architects/designers
Zynk Design Consultants: Architects/designers
Spa software
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Skincare
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Whole body cryotherapy
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