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Les Mills International
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UNITING THE WORLD OF FITNESS
Health Club Management

Health Club Management

features

HCM People: Professor Zhen Yandirector of the Center for Skeletal Muscle Research, University of Virginia

Regular exercise may help people survive COVID-19

Published in Health Club Management 2020 issue 4
Zhen Yan set out to show the physiological impact of exercise on COVID-19 outcomes
Zhen Yan set out to show the physiological impact of exercise on COVID-19 outcomes

Approximately 80 per cent of confirmed COVID-19 patients have mild symptoms, make a good recovery and don’t need respiratory support, while others become extremely unwell and need life support. Professor Zhen Yan at the University of Virginia set out to find out why outcomes are so mixed.

Yan found regular exercise may reduce the risk of complications in people with COVID-19, as well as offering the potential for alternative treatment approaches going forward.

He studied an antioxidant called extracellular superoxide dismutase (EcSOD) that’s released by the muscles and into the bloodstream during exercise.

His work “strongly supports” the possibility that higher levels of EcSOD in the body can prevent or at least reduce the severity of acute respiratory distress syndrome (ARDS) – one of the worst outcomes of the COVID-19 virus.

EcSOD does this by hunting down free radicals, binding to organs and protecting tissues from attack by the virus.

“Our findings strongly support that enhanced EcSOD expression from skeletal muscle…which can be redistributed to lung tissue, could be a viable preventative and therapeutic measure in reducing the risk and severity of ARDS in COVID-19 patients,” he said.

Research suggests that even a single session of exercise increases the production of the antioxidant, prompting Yan to urge people to find ways to exercise, even while maintaining social distancing.

Cardiovascular exercise is thought to drive the highest immediate levels of EcSOD production, however, strength training increases muscle mass, meaning it also plays a part in the equation.

Between three and 17 per cent of people with COVID-19 patients will develop ARDS – this percentage goes up once people are hospitalised to between 20 and 42 per cent, as the more extreme cases succumb to the virus.

“We often say that exercise is medicine. This insight into the role of EcSOD in the body is a perfect example of how we can learn from the biological process of exercise to advance medicine,” Yan said.

“While we strive to learn more about the mysteries of the superb benefits of regular exercise, we don’t have to wait until we know everything before starting to take advantage of this benefit.”

Yan said EcSOD may also prevent multi-organ dysfunction syndrome – in which multiple organs begin to fail.

The antioxidant is also being proposed as a potential therapy for diabetic retinopathy, a complication of diabetes that can lead to blindness.

Low levels of EcSOD are seen in heart disease, kidney failure and osteoarthritis.

Find out more: faculty.virginia.edu/yanlab

Sign up here to get HCM's weekly ezine and every issue of HCM magazine free on digital.
Strength training grows muscle mass, increasing the potential for secreting EcSOD
Strength training grows muscle mass, increasing the potential for secreting EcSOD
https://www.leisureopportunities.co.uk/images/2020/945024_195781.jpg
Regular exercise may reduce the risk of complications in people with COVID-19
Professor Zhen Yan, Center for Skeletal Muscle Research, University of Virginia, covid-19,coronavirus,
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features

HCM People: Professor Zhen Yandirector of the Center for Skeletal Muscle Research, University of Virginia

Regular exercise may help people survive COVID-19

Published in Health Club Management 2020 issue 4
Zhen Yan set out to show the physiological impact of exercise on COVID-19 outcomes
Zhen Yan set out to show the physiological impact of exercise on COVID-19 outcomes

Approximately 80 per cent of confirmed COVID-19 patients have mild symptoms, make a good recovery and don’t need respiratory support, while others become extremely unwell and need life support. Professor Zhen Yan at the University of Virginia set out to find out why outcomes are so mixed.

Yan found regular exercise may reduce the risk of complications in people with COVID-19, as well as offering the potential for alternative treatment approaches going forward.

He studied an antioxidant called extracellular superoxide dismutase (EcSOD) that’s released by the muscles and into the bloodstream during exercise.

His work “strongly supports” the possibility that higher levels of EcSOD in the body can prevent or at least reduce the severity of acute respiratory distress syndrome (ARDS) – one of the worst outcomes of the COVID-19 virus.

EcSOD does this by hunting down free radicals, binding to organs and protecting tissues from attack by the virus.

“Our findings strongly support that enhanced EcSOD expression from skeletal muscle…which can be redistributed to lung tissue, could be a viable preventative and therapeutic measure in reducing the risk and severity of ARDS in COVID-19 patients,” he said.

Research suggests that even a single session of exercise increases the production of the antioxidant, prompting Yan to urge people to find ways to exercise, even while maintaining social distancing.

Cardiovascular exercise is thought to drive the highest immediate levels of EcSOD production, however, strength training increases muscle mass, meaning it also plays a part in the equation.

Between three and 17 per cent of people with COVID-19 patients will develop ARDS – this percentage goes up once people are hospitalised to between 20 and 42 per cent, as the more extreme cases succumb to the virus.

“We often say that exercise is medicine. This insight into the role of EcSOD in the body is a perfect example of how we can learn from the biological process of exercise to advance medicine,” Yan said.

“While we strive to learn more about the mysteries of the superb benefits of regular exercise, we don’t have to wait until we know everything before starting to take advantage of this benefit.”

Yan said EcSOD may also prevent multi-organ dysfunction syndrome – in which multiple organs begin to fail.

The antioxidant is also being proposed as a potential therapy for diabetic retinopathy, a complication of diabetes that can lead to blindness.

Low levels of EcSOD are seen in heart disease, kidney failure and osteoarthritis.

Find out more: faculty.virginia.edu/yanlab

Sign up here to get HCM's weekly ezine and every issue of HCM magazine free on digital.
Strength training grows muscle mass, increasing the potential for secreting EcSOD
Strength training grows muscle mass, increasing the potential for secreting EcSOD
https://www.leisureopportunities.co.uk/images/2020/945024_195781.jpg
Regular exercise may reduce the risk of complications in people with COVID-19
Professor Zhen Yan, Center for Skeletal Muscle Research, University of Virginia, covid-19,coronavirus,
Latest News
People should concentrate on exercise and staying fit – rather than dieting and weight loss ...
Latest News
Sibec Europe, scheduled to take place in Cologne, Germany, from 2 to 5 November 2021, ...
Latest News
Swim England has warned that 2,000 swimming pools could be lost forever unless the government ...
Latest News
Sports Minister, Nigel Huddleston, has joined gym-goers this morning to kick-off the annual National Fitness ...
Latest News
A new high-end workspace, designed for the use of personal trainers, coaches and other health ...
Latest News
VAT reform, adjustments in business rates and a fitness-led high street regeneration push could see ...
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Peloton has completed the merging of its commercial operations with Precor, the equipment brand it ...
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Half of UK adults aren't happy with their physical fitness levels, according to a study ...
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During the pandemic, a digital transformation took off faster than anyone could have predicted with meetings in person cancelled and millions working from home.
Featured supplier news
Featured supplier news: Surge integrates Fisikal with HubSpot to drive business efficiencies and grow revenue
As Surge expands its offer with the launch of a third dedicated Electronic Muscle Stimulation (EMS) studio this summer – this time in Fleet Street, London – the brand reflects on the vital role of its estate wide digital ecosystem, created in partnership with Fisikal, designed to drive business efficiencies and commercial success.
Featured operator news
Featured operator news: Everyone Active bolsters Everyone on Demand and enters second year with five new partnerships
Everyone Active has signed a number of new deals which will see the operator strengthen its digital product offering, Everyone on Demand.
Featured operator news
Featured operator news: Being active helps Parkwood Leisure customers save the NHS £16m
Parkwood Leisure, one of the UK’s leading public leisure facilities operators, helped prevent more than 7,000 cases of stroke, dementia, depression and type 2 diabetes in 2019, saving the NHS £16 million, a new social value report has shown.
Company profiles
Company profile: Orbit4
Orbit4 is the umbrella brand for FitnessCompared, FitnessFinance, WeServiceGymEquipment and WeBuyGymEquipment....
Company profiles
Company profile: Hussle
Hussle exists for two reasons: To increase opportunities for people to engage in physical activity ...
Catalogue Gallery
Click on a catalogue to view it online
Directory
Lockers/interior design
Crown Sports Lockers: Lockers/interior design
Flooring
Total Vibration Solutions / TVS Sports Surfaces: Flooring
Salt therapy products
Saltability: Salt therapy products
Exercise equipment
Power Plate: Exercise equipment
Architects/designers
Zynk Design Consultants: Architects/designers
Fitness equipment
Octane Fitness: Fitness equipment
Whole body cryotherapy
Art of Cryo: Whole body cryotherapy
Independent service & maintenance
Servicesport UK Limited: Independent service & maintenance
Wearable technology solutions
MyZone: Wearable technology solutions
Red Light Therapy
 Red Light Rising: Red Light Therapy
Property & Tenders
Welwyn Garden City
Welwyn Hatfield Borough Council
Property & Tenders
Newport, Shropshire
Lilleshall Sports Academy
Property & Tenders
Diary dates
13-14 Oct 2021
Online,
Diary dates
01-03 Feb 2022
Coventry Building Society Arena, Coventry, United Kingdom
Diary dates
07-10 Apr 2022
Exhibition Centre , Cologne, Germany
Diary dates
15-16 Jun 2022
ExCeL London, London, United Kingdom
Diary dates
01-07 Dec 2022
tbc, Dunedin, New Zealand
Diary dates
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Les Mills International
Les Mills International