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UNITING THE WORLD OF FITNESS
Health Club Management

Health Club Management

features

HCM People: Professor Zhen Yandirector of the Center for Skeletal Muscle Research, University of Virginia

Regular exercise may help people survive COVID-19

Published in Health Club Management 2020 issue 4
Zhen Yan set out to show the physiological impact of exercise on COVID-19 outcomes
Zhen Yan set out to show the physiological impact of exercise on COVID-19 outcomes

Approximately 80 per cent of confirmed COVID-19 patients have mild symptoms, make a good recovery and don’t need respiratory support, while others become extremely unwell and need life support. Professor Zhen Yan at the University of Virginia set out to find out why outcomes are so mixed.

Yan found regular exercise may reduce the risk of complications in people with COVID-19, as well as offering the potential for alternative treatment approaches going forward.

He studied an antioxidant called extracellular superoxide dismutase (EcSOD) that’s released by the muscles and into the bloodstream during exercise.

His work “strongly supports” the possibility that higher levels of EcSOD in the body can prevent or at least reduce the severity of acute respiratory distress syndrome (ARDS) – one of the worst outcomes of the COVID-19 virus.

EcSOD does this by hunting down free radicals, binding to organs and protecting tissues from attack by the virus.

“Our findings strongly support that enhanced EcSOD expression from skeletal muscle…which can be redistributed to lung tissue, could be a viable preventative and therapeutic measure in reducing the risk and severity of ARDS in COVID-19 patients,” he said.

Research suggests that even a single session of exercise increases the production of the antioxidant, prompting Yan to urge people to find ways to exercise, even while maintaining social distancing.

Cardiovascular exercise is thought to drive the highest immediate levels of EcSOD production, however, strength training increases muscle mass, meaning it also plays a part in the equation.

Between three and 17 per cent of people with COVID-19 patients will develop ARDS – this percentage goes up once people are hospitalised to between 20 and 42 per cent, as the more extreme cases succumb to the virus.

“We often say that exercise is medicine. This insight into the role of EcSOD in the body is a perfect example of how we can learn from the biological process of exercise to advance medicine,” Yan said.

“While we strive to learn more about the mysteries of the superb benefits of regular exercise, we don’t have to wait until we know everything before starting to take advantage of this benefit.”

Yan said EcSOD may also prevent multi-organ dysfunction syndrome – in which multiple organs begin to fail.

The antioxidant is also being proposed as a potential therapy for diabetic retinopathy, a complication of diabetes that can lead to blindness.

Low levels of EcSOD are seen in heart disease, kidney failure and osteoarthritis.

Find out more: faculty.virginia.edu/yanlab

Sign up here to get HCM's weekly ezine and every issue of HCM magazine free on digital.
Strength training grows muscle mass, increasing the potential for secreting EcSOD
Strength training grows muscle mass, increasing the potential for secreting EcSOD
https://www.leisureopportunities.co.uk/images/2020/945024_195781.jpg
Regular exercise may reduce the risk of complications in people with COVID-19
Professor Zhen Yan, Center for Skeletal Muscle Research, University of Virginia, covid-19,coronavirus,
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Diary dates
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Online,
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features

HCM People: Professor Zhen Yandirector of the Center for Skeletal Muscle Research, University of Virginia

Regular exercise may help people survive COVID-19

Published in Health Club Management 2020 issue 4
Zhen Yan set out to show the physiological impact of exercise on COVID-19 outcomes
Zhen Yan set out to show the physiological impact of exercise on COVID-19 outcomes

Approximately 80 per cent of confirmed COVID-19 patients have mild symptoms, make a good recovery and don’t need respiratory support, while others become extremely unwell and need life support. Professor Zhen Yan at the University of Virginia set out to find out why outcomes are so mixed.

Yan found regular exercise may reduce the risk of complications in people with COVID-19, as well as offering the potential for alternative treatment approaches going forward.

He studied an antioxidant called extracellular superoxide dismutase (EcSOD) that’s released by the muscles and into the bloodstream during exercise.

His work “strongly supports” the possibility that higher levels of EcSOD in the body can prevent or at least reduce the severity of acute respiratory distress syndrome (ARDS) – one of the worst outcomes of the COVID-19 virus.

EcSOD does this by hunting down free radicals, binding to organs and protecting tissues from attack by the virus.

“Our findings strongly support that enhanced EcSOD expression from skeletal muscle…which can be redistributed to lung tissue, could be a viable preventative and therapeutic measure in reducing the risk and severity of ARDS in COVID-19 patients,” he said.

Research suggests that even a single session of exercise increases the production of the antioxidant, prompting Yan to urge people to find ways to exercise, even while maintaining social distancing.

Cardiovascular exercise is thought to drive the highest immediate levels of EcSOD production, however, strength training increases muscle mass, meaning it also plays a part in the equation.

Between three and 17 per cent of people with COVID-19 patients will develop ARDS – this percentage goes up once people are hospitalised to between 20 and 42 per cent, as the more extreme cases succumb to the virus.

“We often say that exercise is medicine. This insight into the role of EcSOD in the body is a perfect example of how we can learn from the biological process of exercise to advance medicine,” Yan said.

“While we strive to learn more about the mysteries of the superb benefits of regular exercise, we don’t have to wait until we know everything before starting to take advantage of this benefit.”

Yan said EcSOD may also prevent multi-organ dysfunction syndrome – in which multiple organs begin to fail.

The antioxidant is also being proposed as a potential therapy for diabetic retinopathy, a complication of diabetes that can lead to blindness.

Low levels of EcSOD are seen in heart disease, kidney failure and osteoarthritis.

Find out more: faculty.virginia.edu/yanlab

Sign up here to get HCM's weekly ezine and every issue of HCM magazine free on digital.
Strength training grows muscle mass, increasing the potential for secreting EcSOD
Strength training grows muscle mass, increasing the potential for secreting EcSOD
https://www.leisureopportunities.co.uk/images/2020/945024_195781.jpg
Regular exercise may reduce the risk of complications in people with COVID-19
Professor Zhen Yan, Center for Skeletal Muscle Research, University of Virginia, covid-19,coronavirus,
Latest News
Rainer Schaller, founder of budget gym megabrand McFIT, says that the global fitness industry will ...
Latest News
The most high-risk and controversial Olympics of modern times begin today (23 July) in Tokyo, ...
Latest News
Further research into the levels of positive COVID-19 cases among those to have visited fitness ...
Latest News
Planning approval has been granted to what is set to become one of the first ...
Latest News
Digital fitness content provider, Wexer, is launching a new wellness resource on its connected Web ...
Latest News
Leisure-net has revealed plans to transform its active-net business event from an annual face-to-face gathering ...
Latest News
F45's IPO on the New York Stock Exchange (NYSE) has revealed a strong appetite from ...
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A large health club plays a major role in tech giant Microsoft’s recently opened R&D ...
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Featured supplier news
Featured supplier news: Cryotherapy specialists, L&R Kältetechnik, launch new artofcryo.com division
L&R Kältetechnik has launched a new division, named artofcryo.com, after 30 years’ experience with -110 °C electrical solutions.
Featured supplier news
Featured supplier news: How are hundreds of gym operators suddenly saving a lot of money for doing a lot less work?
Let’s talk about Orbit4 – the secret behind successful gyms.
Featured operator news
Featured operator news: Everyone Active bolsters Everyone on Demand and enters second year with five new partnerships
Everyone Active has signed a number of new deals which will see the operator strengthen its digital product offering, Everyone on Demand.
Featured operator news
Featured operator news: Being active helps Parkwood Leisure customers save the NHS £16m
Parkwood Leisure, one of the UK’s leading public leisure facilities operators, helped prevent more than 7,000 cases of stroke, dementia, depression and type 2 diabetes in 2019, saving the NHS £16 million, a new social value report has shown.
Company profiles
Company profile: Merrithew™ - Leaders in Mindful Movement™
Merrithew™ enriches the lives of others with responsible exercise modalities and innovative, multidisciplinary fitness offerings ...
Company profiles
Company profile: Mindbody
Mindbody is the leading technology platform for the wellness industry, featuring an app that allows ...
Catalogue Gallery
Click on a catalogue to view it online
Directory
Fitness equipment
Precor: Fitness equipment
Management software
fibodo Limited: Management software
Salt therapy products
Saltability: Salt therapy products
Uniforms
Service Sport: Uniforms
Spa software
SpaBooker: Spa software
Skincare
Comfort Zone - Davines S.p.A: Skincare
Flooring
Total Vibration Solutions / TVS Sports Surfaces: Flooring
Architects/designers
Zynk Design Consultants: Architects/designers
Red Light Therapy
 Red Light Rising: Red Light Therapy
Independent service & maintenance
Servicesport UK Limited: Independent service & maintenance
Property & Tenders
Newport, Shropshire
Lilleshall Sports Academy
Property & Tenders
Pendine Sands, Carmarthenshire
Carmarthenshire County Council
Property & Tenders
Diary dates
18-19 Sep 2021
Locations worldwide,
Diary dates
21-24 Sep 2021
Messe Stuttgart, Germany
Diary dates
13-14 Oct 2021
Online,
Diary dates
04-07 Nov 2021
Exhibition Centre , Cologne, Germany
Diary dates
01-03 Feb 2022
Coventry Building Society Arena, Coventry, United Kingdom
Diary dates
15-16 Jun 2022
ExCeL London, London, United Kingdom
Diary dates
01-07 Dec 2022
tbc, Dunedin, New Zealand
Diary dates
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