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JP Lennard
JP Lennard
JP Lennard
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UNITING THE WORLD OF FITNESS
Health Club Management

Health Club Management

features

Research: Exercise can counter diabetes damage

Being physically active can heal damage caused by diabetes, enabling the activation of a natural system that grows new blood vessels, according to research in the US

Published in Health Club Management 2022 issue 4
One 45 minute ssession was enough to register a positive impact / Shutterstock/Juice Flair
One 45 minute ssession was enough to register a positive impact / Shutterstock/Juice Flair
Exercise can simulate the growth of new blood vessels when existing ones are ravaged by diabetes

Diabetes not only damages existing blood vessels but also hinders the body’s innate ability to grow new ones in the face of disease and injury.

Scientists at Medical College of Georgia (MCG), however, have found that exercise can help enable angiogenesis – the formation of new blood vessels – which in turn reverses the damage caused by diabetes.

In a study published in The FASEB Journal, a team at MCG’s Vascular Biology Center found the first evidence that in the face of diabetes, even one 45-minute session of moderate-intensity exercise prompts the release of more exosomes into the blood to deliver more of the protein ATP7A directly to cells, which can set angiogenesis in motion. Exosomes are submicroscopic packages filled with biologically active ‘cargo’.

One cardio session
In a sample of healthy 50-something-year-olds, one cardio session increased levels of ATP7A in the exosomes that attached to endothelial cells.

Exercise also increased levels of extracellular superoxide dismutase (SOD3), an important natural antioxidant produced by vascular smooth muscle cells in the walls of blood vessels, as well as skeletal muscle cells, which helps maintain healthy levels of reactive oxygen species or ROS.

ROS is a natural byproduct of our use of oxygen that is an important cell signal, enabling a variety of functions. But in diabetes, high blood sugar levels result in higher ROS levels that instead hinder important normal functions.

Dr Tohru Fukai, MCG vascular biologist and cardiologist and lead author of the study, said: “ATP7A levels are reduced in diabetes and we now have some of the first evidence that exosomes actually impair angiogenesis among those with Type 2 diabetes.

Read the full research report: Exercise improves angiogenic function of circulating exosomes in type 2 diabetes: Role of exosomal SOD3 at www.hcmmag.com/angiogenic

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Exercise can stimulate the growth of new blood vessels when existing ones are ravaged by diabetes, find researchers
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features

Research: Exercise can counter diabetes damage

Being physically active can heal damage caused by diabetes, enabling the activation of a natural system that grows new blood vessels, according to research in the US

Published in Health Club Management 2022 issue 4
One 45 minute ssession was enough to register a positive impact / Shutterstock/Juice Flair
One 45 minute ssession was enough to register a positive impact / Shutterstock/Juice Flair
Exercise can simulate the growth of new blood vessels when existing ones are ravaged by diabetes

Diabetes not only damages existing blood vessels but also hinders the body’s innate ability to grow new ones in the face of disease and injury.

Scientists at Medical College of Georgia (MCG), however, have found that exercise can help enable angiogenesis – the formation of new blood vessels – which in turn reverses the damage caused by diabetes.

In a study published in The FASEB Journal, a team at MCG’s Vascular Biology Center found the first evidence that in the face of diabetes, even one 45-minute session of moderate-intensity exercise prompts the release of more exosomes into the blood to deliver more of the protein ATP7A directly to cells, which can set angiogenesis in motion. Exosomes are submicroscopic packages filled with biologically active ‘cargo’.

One cardio session
In a sample of healthy 50-something-year-olds, one cardio session increased levels of ATP7A in the exosomes that attached to endothelial cells.

Exercise also increased levels of extracellular superoxide dismutase (SOD3), an important natural antioxidant produced by vascular smooth muscle cells in the walls of blood vessels, as well as skeletal muscle cells, which helps maintain healthy levels of reactive oxygen species or ROS.

ROS is a natural byproduct of our use of oxygen that is an important cell signal, enabling a variety of functions. But in diabetes, high blood sugar levels result in higher ROS levels that instead hinder important normal functions.

Dr Tohru Fukai, MCG vascular biologist and cardiologist and lead author of the study, said: “ATP7A levels are reduced in diabetes and we now have some of the first evidence that exosomes actually impair angiogenesis among those with Type 2 diabetes.

Read the full research report: Exercise improves angiogenic function of circulating exosomes in type 2 diabetes: Role of exosomal SOD3 at www.hcmmag.com/angiogenic

https://www.leisureopportunities.co.uk/images/2022/535084_535875.jpg
Exercise can stimulate the growth of new blood vessels when existing ones are ravaged by diabetes, find researchers
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More than one in five (27 per cent) Americans belonged to a health club or ...
Latest News
Ultimate Performance (UP) – the private gym chain and PT business – has opened a ...
Latest News
Luxury hotel chain Mandarin Oriental has launched a new brand called Intelligent Movement to deliver ...
Latest News
Boutique fitness chain 1Rebel opens the doors to its tenth club today (Monday 27 June ...
Latest News
A new report by Deloitte, outlining the social and economic value of the global health ...
Latest News
Barry’s has entered the world of retail, opening a studio in the new Flannels flagship ...
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The London 2012 Olympic legacy investment designed to improve physical education at primary schools has ...
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F45 will be launching its first studio in a hotel in Q3 2022, following a ...
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Premier Global NASM, which is owned by US-based Ascend Learning, has announced it's winding up ...
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David Lloyd has introduced a small-group training programme called Delta to the range of classes ...
Featured supplier news
Featured supplier news: How wearables-driven gamification will boost your business
It’s a known fact that gamification is an effective method to make everyday activities and work more fun.
Featured supplier news
Featured supplier news: It’s nearly time for Elevate 2022!
It’s now just days to go until your leading trade show for the fitness, physical activity and sports therapy industry kicks off in London!
Featured operator news
Featured operator news: New £42m Moorways Sports Village to open on 21 May
Everyone Active will open Moorways Sports Village to the public on Saturday 21 May with a grand opening weekend – in time for the half term holidays.
Featured operator news
Featured operator news: Everyone Active to launch new exercise classes to reduce gender gap
As part of their work to break down the barriers that deter women and girls from participating in sport and physical activity, Everyone Active has teamed up with EMD UK to launch new exercise classes linked to the This Girl Can campaign.
Company profiles
Company profile: Everyone Active
Everyone Active operates leisure centres in partnership with local councils across the UK. Today, Everyone ...
Company profiles
Company profile: We Work Well Inc
We Work Well is a global premier hosted buyer event company, connecting high-level executives from ...
Catalogue Gallery
Click on a catalogue to view it online
Directory
Lockers/interior design
Crown Sports Lockers: Lockers/interior design
Management software
Premier Software Solutions: Management software
Flooring
Total Vibration Solutions / TVS Sports Surfaces: Flooring
On demand
Fitness On Demand: On demand
Skincare
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Architects/designers
Zynk Design Consultants: Architects/designers
Whole body cryotherapy
Art of Cryo: Whole body cryotherapy
Salt therapy products
Saltability: Salt therapy products
Fitness equipment
A Panatta Sport Srl: Fitness equipment
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MyZone: Wearable technology solutions
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Pendine Sands, Carmarthenshire
Carmarthenshire County Council
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Runcorn
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The ICC, Birmingham, Birmingham , United Kingdom
Diary dates
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Diary dates
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