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JP Lennard
JP Lennard
JP Lennard
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UNITING THE WORLD OF FITNESS
Health Club Management

Health Club Management

features

Research: Exercise can counter diabetes damage

Being physically active can heal damage caused by diabetes, enabling the activation of a natural system that grows new blood vessels, according to research in the US

Published in Health Club Management 2022 issue 4
One 45 minute ssession was enough to register a positive impact / Shutterstock/Juice Flair
One 45 minute ssession was enough to register a positive impact / Shutterstock/Juice Flair
Exercise can simulate the growth of new blood vessels when existing ones are ravaged by diabetes

Diabetes not only damages existing blood vessels but also hinders the body’s innate ability to grow new ones in the face of disease and injury.

Scientists at Medical College of Georgia (MCG), however, have found that exercise can help enable angiogenesis – the formation of new blood vessels – which in turn reverses the damage caused by diabetes.

In a study published in The FASEB Journal, a team at MCG’s Vascular Biology Center found the first evidence that in the face of diabetes, even one 45-minute session of moderate-intensity exercise prompts the release of more exosomes into the blood to deliver more of the protein ATP7A directly to cells, which can set angiogenesis in motion. Exosomes are submicroscopic packages filled with biologically active ‘cargo’.

One cardio session
In a sample of healthy 50-something-year-olds, one cardio session increased levels of ATP7A in the exosomes that attached to endothelial cells.

Exercise also increased levels of extracellular superoxide dismutase (SOD3), an important natural antioxidant produced by vascular smooth muscle cells in the walls of blood vessels, as well as skeletal muscle cells, which helps maintain healthy levels of reactive oxygen species or ROS.

ROS is a natural byproduct of our use of oxygen that is an important cell signal, enabling a variety of functions. But in diabetes, high blood sugar levels result in higher ROS levels that instead hinder important normal functions.

Dr Tohru Fukai, MCG vascular biologist and cardiologist and lead author of the study, said: “ATP7A levels are reduced in diabetes and we now have some of the first evidence that exosomes actually impair angiogenesis among those with Type 2 diabetes.

Read the full research report: Exercise improves angiogenic function of circulating exosomes in type 2 diabetes: Role of exosomal SOD3 at www.hcmmag.com/angiogenic

https://www.leisureopportunities.co.uk/images/2022/535084_535875.jpg
Exercise can stimulate the growth of new blood vessels when existing ones are ravaged by diabetes, find researchers
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Ibiza, Ibiza, Spain
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01-07 Dec 2022
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features

Research: Exercise can counter diabetes damage

Being physically active can heal damage caused by diabetes, enabling the activation of a natural system that grows new blood vessels, according to research in the US

Published in Health Club Management 2022 issue 4
One 45 minute ssession was enough to register a positive impact / Shutterstock/Juice Flair
One 45 minute ssession was enough to register a positive impact / Shutterstock/Juice Flair
Exercise can simulate the growth of new blood vessels when existing ones are ravaged by diabetes

Diabetes not only damages existing blood vessels but also hinders the body’s innate ability to grow new ones in the face of disease and injury.

Scientists at Medical College of Georgia (MCG), however, have found that exercise can help enable angiogenesis – the formation of new blood vessels – which in turn reverses the damage caused by diabetes.

In a study published in The FASEB Journal, a team at MCG’s Vascular Biology Center found the first evidence that in the face of diabetes, even one 45-minute session of moderate-intensity exercise prompts the release of more exosomes into the blood to deliver more of the protein ATP7A directly to cells, which can set angiogenesis in motion. Exosomes are submicroscopic packages filled with biologically active ‘cargo’.

One cardio session
In a sample of healthy 50-something-year-olds, one cardio session increased levels of ATP7A in the exosomes that attached to endothelial cells.

Exercise also increased levels of extracellular superoxide dismutase (SOD3), an important natural antioxidant produced by vascular smooth muscle cells in the walls of blood vessels, as well as skeletal muscle cells, which helps maintain healthy levels of reactive oxygen species or ROS.

ROS is a natural byproduct of our use of oxygen that is an important cell signal, enabling a variety of functions. But in diabetes, high blood sugar levels result in higher ROS levels that instead hinder important normal functions.

Dr Tohru Fukai, MCG vascular biologist and cardiologist and lead author of the study, said: “ATP7A levels are reduced in diabetes and we now have some of the first evidence that exosomes actually impair angiogenesis among those with Type 2 diabetes.

Read the full research report: Exercise improves angiogenic function of circulating exosomes in type 2 diabetes: Role of exosomal SOD3 at www.hcmmag.com/angiogenic

https://www.leisureopportunities.co.uk/images/2022/535084_535875.jpg
Exercise can stimulate the growth of new blood vessels when existing ones are ravaged by diabetes, find researchers
Latest News
The Leisure Database Company (TLDB) has revealed its State of the Fitness Industry Report UK ...
Latest News
The Gym Group’s (TGG) plans and profit forecasts were presented to analysts and investors during ...
Latest News
A new physical activity programme called Big Sister has been launched in the UK to ...
Latest News
Go Fit has been selected by the United Nations Economic Commission for Europe (UNECE) as ...
Latest News
Ness, a US startup that is developing a range of wellness-driven credit cards, has launched ...
Latest News
Following a history of supporting US military and service members, F45 has announced a new ...
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Hyatt is piloting private gyms in five of its US hotels as part of its ...
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A young girl has died following an incident at the David Lloyd gym at Capability ...
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Featured supplier news
Featured supplier news: Thousands flock to register for Elevate 2022 in London this summer
The health and fitness industry is eagerly awaiting the return of Elevate, which will take place on 15-16 June 2022 at ExCeL London.
Featured supplier news
Featured supplier news: What’s the first thing you think about when selling gym equipment?
According to our poll the first thing 80 per cent of operators and gym owners think about when it’s time to sell gym equipment is how much your equipment is worth.
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Featured operator news: Serco Leisure wins 10-year Mansfield contract
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As part of their work to break down the barriers that deter women and girls from participating in sport and physical activity, Everyone Active has teamed up with EMD UK to launch new exercise classes linked to the This Girl Can campaign.
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Company profile: Life Fitness
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Company profiles
Company profile: Mindbody
Mindbody is the leading technology platform for the wellness industry, featuring an app that allows ...
Catalogue Gallery
Click on a catalogue to view it online
Directory
Architects/designers
Zynk Design Consultants: Architects/designers
Flooring
Total Vibration Solutions / TVS Sports Surfaces: Flooring
Skincare
Comfort Zone - Davines S.p.A: Skincare
Wearable technology solutions
MyZone: Wearable technology solutions
trade associations
International SPA Association - iSPA: trade associations
Whole body cryotherapy
Zimmer MedizinSysteme GmbH / icelab: Whole body cryotherapy
On demand
Fitness On Demand: On demand
Spa software
SpaBooker: Spa software
Fitness equipment
A Panatta Sport Srl: Fitness equipment
Management software
Premier Software Solutions: Management software
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Pendine Sands, Carmarthenshire
Carmarthenshire County Council
Property & Tenders
Runcorn
Halton Borough Council
Property & Tenders
Diary dates
15-16 Jun 2022
ExCeL London, London, United Kingdom
Diary dates
30-30 Jun 2022
The ICC, Birmingham, Birmingham , United Kingdom
Diary dates
12-13 Sep 2022
Wyndham Lake Buena Vista Disney Springs® Resort, Lake Buena Vista, United States
Diary dates
25-28 Oct 2022
Messe Stuttgart, Germany
Diary dates
25-28 Oct 2022
Ibiza, Ibiza, Spain
Diary dates
01-07 Dec 2022
tbc, Dunedin, New Zealand
Diary dates
17-18 Mar 2023
Tobacco Dock, London, United Kingdom
Diary dates
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